Local recurrence after radical prostatectomy: characteristics in size, location, and relationship to prostate-specific antigen and surgical margins

Urology
J A ConnollyP R Carroll

Abstract

To define the sonographic characteristics of local cancer recurrence after radical prostatectomy. in 114 patients with an elevated prostate-specific antigen (PSA) and negative bone scan, 156 ultrasound-guided prostate fossa biopsies were carried out. in 53.5%, biopsy proved local recurrence. More than one ultrasound-guided biopsy session was required to make the diagnosis in 33% of patients. Local recurrence was seen on ultrasound at the anastomotic site (66%), the bladder neck (16%), and posterior to the trigone (13%). in 5% of patients there was a normal-appearing anastomotic site. Transrectal ultrasound was greater than 90% sensitive in detecting local recurrence, but lacked specificity. Examination of the radical prostatectomy specimens in patients with local recurrence showed positive surgical margins in 66% and organ-confined disease in 20%. Transrectal ultrasonography is a useful adjunct to PSA and digital rectal examination in the detection of local recurrences following radical prostatectomy.

References

Oct 1, 1990·The Journal of Urology·D J LightnerL Moore
Jun 1, 1991·The Journal of Urology·R A MortonP C Walsh
Dec 1, 1972·The Journal of Urology·D L McCullough, W F Leadbetter

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Citations

Sep 11, 2007·European Journal of Nuclear Medicine and Molecular Imaging·Sven N ReskeGerhard Glatting
Sep 25, 2007·European Journal of Nuclear Medicine and Molecular Imaging·B J KrauseM Schwaiger
Jun 27, 2002·Current Urology Reports·C R Pound, A W Partin
May 27, 2004·Current Urology Reports·Masood A Khan, Alan W Partin
Aug 27, 2013·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·J KhalifaR de Crevoisier
Apr 2, 2003·Urology·Douglas ScherrUNKNOWN National Comprehensive Cancer Network
Mar 1, 1997·Urology·P R CarrollM Roach
Dec 19, 2003·The Urologic Clinics of North America·Joel B Nelson, Herbert Lepor
Feb 23, 1999·The Urologic Clinics of North America·D K OrnsteinG L Andriole
Sep 10, 2003·Current Problems in Cancer·Judd W Moul
Nov 3, 2001·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·C ParkerC Catton
Nov 5, 2003·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·George RodriguesGerard Morton
Feb 21, 2007·Prostate Cancer and Prostatic Diseases·A D StockdaleA R E Blacklock
Jan 9, 2008·Prostate Cancer and Prostatic Diseases·C GrecoO Tamburrini
Jun 21, 2002·The Cancer Journal·Steven E Schild
Apr 24, 2008·AJR. American Journal of Roentgenology·Emanuele CascianiGian Franco Gualdi
Jan 30, 1999·Radiographics : a Review Publication of the Radiological Society of North America, Inc·C A LawtonD A Kuban
Nov 25, 2011·Future Oncology·Mark V MishraTimothy N Showalter
May 17, 2014·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·Linda J BellAndrew Kneebone
Apr 7, 2010·Cancer Research and Treatment : Official Journal of Korean Cancer Association·Richard Choo
Nov 7, 2012·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·D BottkeT Wiegel
Apr 27, 2013·Current Opinion in Urology·Detlef BartkowiakThomas Wiegel
Nov 6, 2013·Hematology/oncology Clinics of North America·Richard Khor, Scott Williams
May 20, 2016·Abdominal Radiology·Eric J MayAdam T Froemming
Apr 28, 2009·International Journal of Radiation Oncology, Biology, Physics·Jeff M MichalskiCynthia Ménard
Mar 26, 2004·Clinical Prostate Cancer·Robert A Zimmerman, Daniel J Culkin

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