Local recurrence after transanal endoscopic microsurgery for rectal polyps and early cancers

Annals of Surgical Oncology
Sabha GanaiAlbert I Alexander

Abstract

Transanal endoscopic microsurgery (TEM) allows for local excision of rectal neoplasms with greater exposure than transanal excision and less morbidity than transabdominal approaches. This study examines the implications of the procedure with respect to predictors of recurrence. We performed a retrospective analysis of 144 consecutive TEMs from 1993 to 2004. The study comprises 107 patients presenting for TEM with benign disease and 32 patients with cancer. Patients had a mean age of 64+/-14 (SD) years. TEM was performed for recurrent lesions in 17% of cases. Pathologic classification of the lesions after TEM was benign adenoma in 45%, adenoma with high-grade dysplasia (HGD) in 17%, cancer in 33%, and other in 4%. Complications occurred in 10%, and local recurrence occurred in 15% of patients. Median follow-up was 44 months, with a median time to recurrence of 14 months. Positive margins did not influence lesion recurrence. Recurrence of cancers correlated with the depth of tumor invasion (P<.05). On multivariate analysis, independent predictors of recurrence were lesion size and the presence of HGD within adenomas (P<.05). Five-year neoplastic recurrence probabilities were 11% for benign adenomas, 35% for adenomas with HGD, and...Continue Reading

References

May 1, 1992·World Journal of Surgery·S Nivatvongs, B G Wolff
Jan 1, 1992·American Journal of Surgery·G BuessH D Becker
May 1, 1991·International Journal of Colorectal Disease·F P Gall
Sep 1, 1990·American Journal of Surgery·R A GrahamJ M Jessup
Apr 1, 1986·International Journal of Colorectal Disease·P Hermanek, F P Gall
Sep 1, 1973·The British Journal of Surgery·A G Parks, A E Stuart
Feb 1, 1984·Diseases of the Colon and Rectum·M GriggE S Hughes
Sep 1, 1982·American Journal of Surgery·K HojoY Moriya
Apr 1, 1995·The British Journal of Surgery·J Mayer, N J Mortensen
Jan 1, 1995·Surgical Endoscopy·K S Khanduja
Jan 1, 1994·Diseases of the Colon and Rectum·T J SaclaridesS G Economou
Feb 1, 1996·The British Journal of Surgery·R J SteeleJ H Scholefield
Aug 1, 1996·Diseases of the Colon and Rectum·B MentgesH D Becker
Feb 1, 1997·The Surgical Clinics of North America·T J Saclarides
Jan 4, 1998·Diseases of the Colon and Rectum·P J SitzlerA P Leong
Jun 24, 1998·Archives of Surgery·T J Saclarides
Aug 24, 1999·Annals of Surgical Oncology·G D SteeleR J Mayer
Mar 14, 2000·Annals of Surgery·J Garcia-AguilarD A Rothenberger
May 29, 2000·Diseases of the Colon and Rectum·D Lev-CheloucheM J Rabau
Aug 19, 2000·Diseases of the Colon and Rectum·A MellgrenJ García-Aguilar
Oct 26, 2000·Hospital Medicine·H SeehraM J Hershman
Feb 20, 2002·Diseases of the Colon and Rectum·Riccardo NascimbeniDirk R Larson
Oct 9, 2002·Annals of Surgery·Philip B PatyW Douglas Wong
Dec 18, 2002·ANZ Journal of Surgery·K Chip FarmerAdrian Polglase
Jan 3, 2003·Endoscopy·J H Bond
May 10, 2003·Surgical Endoscopy·C CocilovoJ Douglas
Nov 25, 2003·ANZ Journal of Surgery·James M Church
Jun 24, 2004·Journal of Gastroenterology and Hepatology·Cameron PlatellGregory Makin
Sep 1, 2004·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·G DafnisW Graf
Sep 1, 2004·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·P PalmaS Post
Dec 29, 2004·Diseases of the Colon and Rectum·Riccardo NascimbeniLawrence J Burgart
Dec 29, 2004·Diseases of the Colon and Rectum·D GopaulPhilip H Gordon
Mar 16, 2005·Diseases of the Colon and Rectum·Khaled M MadboulyIan C Lavery
Dec 22, 2005·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Sabha GanaiRichard B Wait

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Citations

Jul 6, 2014·International Journal of Colorectal Disease·Hideaki MiyamotoKazuhiro Kaneko
Nov 16, 2013·Surgical Endoscopy·Fábio Shiguehissa KawagutiFauze Maluf-Filho
Aug 25, 2009·World Journal of Gastroenterology : WJG·Damian Casadesus
Jun 2, 2009·Techniques in Coloproctology·Andre Roncon DiasIvan Cecconello
Jun 28, 2011·Surgical Endoscopy·R SiegelUNKNOWN European Association for Endoscopic Surgery (EAES)
Apr 6, 2012·Surgical Endoscopy·Marco Ettore AllaixMario Morino
Dec 13, 2012·Surgical Endoscopy·Pamela KoglerMatthias Zitt
Nov 6, 2009·International Journal of Colorectal Disease·Thomas Borschitz, Ralf Kiesslich
May 10, 2011·International Journal of Colorectal Disease·Myles R JoyceFrank B V Keane
Aug 23, 2008·Annals of Surgical Oncology·Thomas BorschitzTheodor Junginger
Dec 2, 2009·Abdominal Imaging·Ali AhmetoğluFeyyaz Ozdemir
Sep 14, 2010·Surgical Oncology·Erwin Rieder, Lee L Swanstrom
Oct 16, 2007·American Journal of Surgery·Emmanouil ZacharakisAra Darzi
Jan 25, 2013·Case Reports in Surgery·Rutger J FrankenEric J Derksen
Jul 5, 2007·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·P A WhitehouseJ N L Simson
Aug 13, 2011·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·A S KumarL E Smith
Aug 11, 2015·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Nidal IssaEldad Powsner
Dec 20, 2016·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Nida IssaWisam Khoury
Jan 26, 2010·Surgical Innovation·Joseph A Trunzo, Conor P Delaney
Oct 26, 2018·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Michał SpychalskiAdam Dziki
Jan 31, 2009·Acta Oncologica·Gunnar BaatrupArild Nesbakken
Mar 21, 2009·Expert Review of Molecular Diagnostics·Kjetil SøreideHartwig Kørner
May 11, 2019·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·G M de Jong, N Hugen
Apr 4, 2012·Diseases of the Colon and Rectum·Francesco StipaAntonio Burza
Jul 15, 2015·World Journal of Gastroenterology : WJG·Wolfgang B GaertnerGenevieve B Melton
Dec 17, 2009·Diseases of the Colon and Rectum·Ben M TsaiAnders Mellgren
Apr 12, 2011·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Emily SteinhagenJosé G Guillem
Sep 24, 2020·Acta Cirúrgica Brasileira·Roberta Denise Alkmin Lopes de LimaJosé Joaquim Ribeiro da Rocha
Jul 9, 2008·Acta Oncologica·Thomas BorschitzTheodor Junginger
Jun 8, 2011·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Yanjie QiJohn R T Monson
Oct 26, 2013·British Journal of Hospital Medicine·Michael J HershmanAwais Ahmed
May 1, 2009·Diseases of the Colon and Rectum·Garrett M NashPhilip B Paty
Oct 5, 2016·Molecular and Clinical Oncology·Shingo NouraMasayoshi Yasui
Oct 23, 2020·Journal of Gastroenterology and Hepatology·Cintia Mayumi Sakurai KimuraFauze Maluf-Filho

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