Local recurrence following treatment for breast cancer with an endoscopic nipple-sparing mastectomy

Breast Cancer : the Journal of the Japanese Breast Cancer Society
Naomi SakamotoKazuei Hoshi

Abstract

Endoscopic nipple-sparing mastectomy (E-NSM) has been reportedly associated with smaller scars and greater patient satisfaction; however, long-term results of this procedure have not been made. The purpose of this retrospective study was to investigate the local recurrence (LR) rate and factors associated with it after E-NSM and to examine the oncologic safety of this procedure. We reviewed the medical records of a total of 421 breasts in 404 patients who underwent E-NSM to investigate the LR rate and the factors associated with it. The clinico-pathological features and the treatment and outcomes of the patients with LRs were also examined. Eleven breasts (2.6 %) in 11 patients presented with LR as the first site of recurrence after a median follow-up time of 61 months. Among the 11 LRs, 9 patients presented with LR only, 1 patient exhibited regional lymph node recurrence, and 1 patient exhibited distant metastasis. The median time from surgery until LR was 25 months. Eight LRs developed near the original tumor site. The risk factors for LR in a multivariate analysis were a younger age of less than 40 years (p = 0.02), Stage III tumor (p = 0.01), and an inadequate surgical margin (p = 0.001). After the treatment, 6 patients had...Continue Reading

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Citations

Feb 22, 2018·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Youichi MachidaEisuke Fukuma
Jul 15, 2020·Breast Cancer Research and Treatment·Orit Kaidar-PersonLiesbeth J Boersma
Sep 11, 2020·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·James BundredNigel Bundred

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