Local treatment of metastases from differentiated thyroid cancer

Annales d'endocrinologie
F BonichonJ Palussière

Abstract

To study the various local treatments available for thyroid cancer metastases, investigate techniques and assess their advantages and limitations and roles in the overall treatment strategy for metastatic disease. We investigated metastases surgery, external radiation therapy, embolization, chemoembolization, cementoplasty, radiofrequency ablation and cryotherapy, describing techniques, advantages and drawbacks and possible complications. Indications were reviewed according to metastases location, and the roles of the various techniques are discussed in the overall treatment strategy for thyroid cancer metastases. Despite the advent of new targeted therapies, local treatment still has an important role to play: either palliative or, in oligometastatic involvement, curative. Even in extensive disease, it may allow postponement of tyrosine kinase inhibitor therapy, which, once initiated, has to be continued life-long, is expensive and is not free of side-effects.

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Nov 10, 2017·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·X ZhangH Lai
May 10, 2020·Cardiovascular and Interventional Radiology·Laura CrocettiFrancesco Paolo Tarantino
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Jul 29, 2017·Expert Review of Anticancer Therapy·Sarah N HamiltonJonn Wu
Apr 3, 2021·Therapeutic Advances in Endocrinology and Metabolism·Latoya A Stewart, Jennifer H Kuo

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