Local treatment of pulmonary metastases: from open resection to minimally invasive approach? Less morbidity, comparable local control.

Surgical Endoscopy
Erik M von MeyenfeldtHouke M Klomp

Abstract

The level of evidence for efficacy of local treatment of pulmonary metastases is low; therefore, complication rates should be minimized. Minimally invasive techniques may have the potential to reduce morbidity but potentially lead to more local and/or ipsilateral recurrences. The objective of this study was to evaluate the introduction of a new treatment strategy incorporating the increased use of video-assisted thoracic surgery (VATS) and radiofrequency ablation (RFA), weighing complications against recurrence rates. We retrospectively reviewed results of all local treatment of pulmonary metastases in the Netherlands Cancer Institute from 2002 to 2007. Each of 158 identified interventions was analyzed separately to retrieve procedure-related data. Overall survival data were analyzed per patient. To evaluate the introduction of a strategy incorporating minimally invasive techniques, the study period was split in two (before and after the introduction of this strategy in July 2004). In Strategy I, 47 interventions (2 VATS, no RFA) were performed in 37 patients; in Strategy II 111 interventions (51 VATS and RFA) in 86 patients. Metastases of a variety of primary tumors were treated. Median hospital stay was shorter (5 vs. 7 days)...Continue Reading

References

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Citations

Feb 22, 2014·Critical Reviews in Oncology/hematology·C Florescu, J Thariat
May 20, 2015·Diagnostic and Interventional Imaging·T de BaereF Deschamps
Mar 27, 2018·Future Oncology·Xu Shan SunJuliette Thariat
Jan 9, 2021·Frontiers in Oncology·Petr SzturzJan B Vermorken

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