PMID: 595774Nov 1, 1977

Local ventricular wall motion, local myocardial flow, and blood flow distribution in a poststenotic myocardial region in patients with coronary heart disease (author's transl)

Zeitschrift für Kardiologie
H SimonN Hahn

Abstract

In 10 patients with coronary heart disease, local ventricular wall motion, local poststenotic flow, and distribution of myocardial perfusion were determined in the underperfused myocardium before and after 8 mg of Oxyfedrin intravenously. In 8 of the 10 patients there was a uniform reaction consisting of an improvement of wall motion, increase in flow, and homogeneity of flow distribution. These parallel changes of local wall movement and local blood flow in a poststenotic underperfused part of the myocardium can most probably be explained by the positively inotropic action of Oxyfedrin with a consecutive increase in blood flow. The results show that a therapeutic affect in patients with a coronary stenosis less than 60% in the left descending artery can be obtained with a positively inotropic substance.

Related Concepts

Diastolic Blood Pressure
Stenosis
Coronary Heart Disease
Sinus Node Artery
Pulse Rate
Left Ventricular Structure
Myocardial Contraction
Myofedrin
Regional Blood Flow

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