Localization of a gene for non-syndromic hearing loss (DFNA5) to chromosome 7p15

Human Molecular Genetics
G van CampR R Frants

Abstract

Progressive hearing loss affects approximately 50% of the elderly by the age of 80, and is most likely caused by an interaction of genetic and environmental factors. Identification of the genes responsible for hereditary hearing loss is therefore important. Families with pure genetic degenerative hearing disorders may be helpful as the same genes may be also involved in age-related hearing loss in general. In this study we have performed a genome search in an extended Dutch family with autosomal dominant progressive hearing loss starting in the high frequencies. The gene causing hearing loss in this family was localized to the short arm of chromosome 7, in a 15 cM interval between markers D7S493 and D7S632.

Citations

Jul 19, 2005·Neurobiology of Disease·Lut Van LaerGuy Van Camp
Jan 3, 1997·International Journal of Pediatric Otorhinolaryngology·C StinckensC Cremers
Aug 1, 1996·Current Opinion in Neurobiology·K P Steel, S D Brown
May 20, 1999·Clinical Genetics·N G Robertson, C C Morton
Jul 19, 2002·Clinical Genetics·M B Petersen
Nov 17, 2009·Journal of Human Genetics·Hong-Joon ParkUn-Kyung Kim
Feb 7, 2009·Journal of Human Genetics·Xiao Mei OuyangXue Zhong Liu
Apr 13, 2000·The New England Journal of Medicine·P J Willems
Oct 7, 2003·Annual Review of Genomics and Human Genetics·Thomas B Friedman, Andrew J Griffith
Feb 3, 2000·Proceedings of the National Academy of Sciences of the United States of America·X ZhouP A Marks
Mar 19, 2008·Biochemical and Biophysical Research Communications·Myoung Sook KimDavid Sidransky
Jul 10, 2007·The Journal of Steroid Biochemistry and Molecular Biology·M S WebbE Brad Thompson
Feb 11, 2014·Annals of Human Genetics·Ayako NishioKen Kitamura
Jun 24, 2003·Annales de génétique·V S TonkGopalrao V N Velagaleti
Sep 15, 2015·Chinese Medical Journal·Mei-Na Li-YangGuang-Qian Xing
Nov 9, 2001·Annual Review of Genetics·C PetitJ P Hardelin
Jul 20, 2002·The Annals of Otology, Rhinology, and Laryngology·Els M R De LeenheerCor W R J Cremers
Apr 26, 2012·The Annals of Otology, Rhinology, and Laryngology·Ken Op de BeeckGuy Van Camp
Sep 18, 2001·Clinical Otolaryngology and Allied Sciences·R J EnsinkC W Cremers
Jan 3, 2019·Genomics & Informatics·Nathanial T Carpena, Min Young Lee
Sep 26, 2001·European Journal of Human Genetics : EJHG·M ManginoB Dallapiccola
Oct 15, 1998·Nature Genetics·L Van LaerG Van Camp
Apr 2, 2015·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Bong Jik KimByung Yoon Choi
Apr 3, 2020·Journal of Cell Communication and Signaling·Danbin WuMaojuan Guo
Apr 4, 2020·The Laryngoscope·Shadi AhmadmehrabiDaniel J Rader
Apr 16, 2020·Acta Biochimica Et Biophysica Sinica·Zengzhang ZhengXing Liu
Aug 7, 2021·Journal of Molecular Biology·Christopher B RyderDerek W Abbott

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