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Localization of a highly immunogenic region of carboxypeptidase A recognized by three different monoclonal antibodies and their use in the detection of subtle conformational alterations in this enzyme region

Biochemistry

Feb 7, 1989

Beka SolomonGideon Fleminger

PMID: 2469466

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Abstract

Three murine monoclonal antibodies (mAb 100, 104, and 121) elicited against carboxypeptidase A (CPA) were prepared and characterized. All three mAbs recognize the same or partially overlapping sites of CPA. This is corroborated by the lack of antibody additivity in the ELISA assay carri...read more

Mentioned in this Paper

Monoclonal antibodies, antineoplastic
Enzymes, antithrombotic
Enzyme-Linked Immunosorbent Assay
Enzymes, peripheral vasodilators
Homologous Gene
Antigen-Antibody Reactions
Immunoblotting, Reverse
Establishment and Maintenance of Localization
Cross Reactions
Carboxypeptidase B
1
Paper Details
References
  • References25
  • Citations9
123
  • References25
  • Citations9
1

Localization of a highly immunogenic region of carboxypeptidase A recognized by three different monoclonal antibodies and their use in the detection of subtle conformational alterations in this enzyme region

Biochemistry

Feb 7, 1989

Beka SolomonGideon Fleminger

PMID: 2469466

DOI:

Abstract

Three murine monoclonal antibodies (mAb 100, 104, and 121) elicited against carboxypeptidase A (CPA) were prepared and characterized. All three mAbs recognize the same or partially overlapping sites of CPA. This is corroborated by the lack of antibody additivity in the ELISA assay carri...read more

Mentioned in this Paper

Monoclonal antibodies, antineoplastic
Enzymes, antithrombotic
Enzyme-Linked Immunosorbent Assay
Enzymes, peripheral vasodilators
Homologous Gene
1

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Paper Details
References
  • References25
  • Citations9
123
  • References25
  • Citations9
1

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