PMID: 7518164DOI: 10.1006/viro.1994.1410Aug 1, 1994Paper
Localization of a neutralizing epitope on the envelope protein of dengue virus type 2
Virology
B LinP J Wright
Abstract
Two neutralization-resistant variants of dengue virus type 2 were selected using the neutralizing monoclonal antibody G8D11. Virus N-GV4 was derived from the New Guinea C strain and virus P-GV3 from the PUO-218 strain. Both variants had an identical change at nucleotide 919 in the E gene, causing a substitution of glutamic acid for lysine at residue 307 in the E glycoprotein. The substitution abolished the ability of antibody G8D11 to bind to the E glycoprotein in radioimmunoprecipitation experiments. The epitope was sensitive to treatment with SDS and was dependent on the formation of a disulfide bridge. This dependency was determined by mutagenesis of Cys residues 11 and 12 in the E glycoprotein.
Citations
Aug 1, 1997·Nature Medicine·Y ChenR M Marks
Apr 27, 2005·Nature Medicine·Theodore OliphantMichael S Diamond
Dec 27, 2007·Viral Immunology·Georgios Amexis, Neal S Young
Sep 21, 2007·Journal of Virology·Soila Sukupolvi-PettyMichael S Diamond
Jun 20, 2008·Journal of Virology·Gregory D GromowskiAlan D T Barrett
Sep 16, 2006·Journal of Virology·Melanie A Samuel, Michael S Diamond
Oct 13, 2006·Journal of Virology·Theodore OliphantMichael S Diamond
Oct 29, 2010·Journal of Virology·Claire M MidgleyGavin R Screaton
Jan 11, 2013·Journal of Virology·Laura J WhiteRobert E Johnston
Sep 23, 2000·Journal of Virology·C W MandlF X Heinz
Jan 29, 2003·Journal of Virology·Cheng-Wen Lin, Suh-Chin Wu
Feb 14, 2004·Journal of Virology·John T RoehrigGwong-Jen J Chang
Dec 23, 2004·Journal of Virology·Yorgo ModisStephen C Harrison
Nov 21, 2013·MBio·Scott A SmithJames E Crowe
In-depth analysis of the antibody response of individuals exposed to primary dengue virus infection.
Jun 30, 2011·PLoS Neglected Tropical Diseases·Ruklanthi de AlwisAravinda M de Silva
Apr 2, 2009·PloS One·Wayne D CrillGwong-Jen J Chang
Apr 7, 2010·PLoS Pathogens·Bimmi ShresthaMichael S Diamond
Mar 6, 2013·PLoS Pathogens·Katherine L WilliamsEva Harris
Nov 26, 2005·Expert Review of Anti-infective Therapy·Michael S Diamond
Jan 30, 2010·Expert Review of Vaccines·Maria G GuzmanGerardo Guillén
Jun 9, 2007·Expert Opinion on Biological Therapy·Theodore Oliphant, Michael S Diamond
Nov 17, 2012·Vaccine·Jing YeShengbo Cao
Sep 8, 2010·Biologicals : Journal of the International Association of Biological Standardization·Juliana Helena ChávezLuiz Tadeu Moraes Figueiredo
Aug 12, 2009·Vaccine·Saima KhanamSathyamangalam Swaminathan
Jul 1, 2008·Antiviral Research·Rushika PereraRichard J Kuhn
Jan 14, 2010·Biopolymers·Heng-Li ChenJya-Wei Cheng
Sep 14, 2010·Virology·Gregory D GromowskiAlan D T Barrett
May 15, 1998·Virology·K D RymanA D Barrett
Aug 30, 2005·Microbes and Infection·Mohan Babu AppaiahgariSudhanshu Vrati
Jun 19, 2008·The Journal of General Virology·Andrew K I Falconar
Jun 21, 2014·The Journal of General Virology·Peng-Yeh LaiHau-Ren Chen
Oct 1, 2011·The Journal of General Virology·Daniel WattersonPaul R Young
Apr 11, 2013·Virology·John T RoehrigClaire Y-H Huang
Jul 11, 1998·Virology·J T RoehrigR G Kelly
Sep 29, 2012·Journal of Virological Methods·Eliseu Soares de Oliveira RochaErna Geessien Kroon
Aug 28, 2007·Virology·Gregory D Gromowski, Alan D T Barrett
Epitopes on the dengue 1 virus envelope protein recognized by neutralizing IgM monoclonal antibodies
Feb 13, 2001·Virology·D W Beasley, J G Aaskov
Mar 31, 2007·Virology·David E VolkDavid G Gorenstein
Jul 28, 2009·Virology·W M P B WahalaAravinda M de Silva
Apr 28, 2012·Virology·Katherine L WilliamsEva Harris
Mar 27, 2015·PloS One·Hapuarachchige Chanditha HapuarachchiYee Sin Leo
Sep 6, 2001·Journal of Medical Virology·S M LokJ Aaskov
Feb 23, 2018·Applied Microbiology and Biotechnology·Hossein FahimiMajid Sadeghizadeh
Jan 4, 2018·International Journal of Molecular Sciences·Haiyan SunHuafang Lai
Feb 24, 2001·Viral Immunology·S LustigM Halevy
Jun 1, 2012·Journal of Virology·Poornima ParameswaranMatthew R Henn
Aug 8, 2014·Journal of Virology·Scott A SmithJames E Crowe
Analysis of functional epitopes on the dengue 2 envelope (E) protein using monoclonal IgM antibodies
Jan 1, 1995·Archives of Virology·Z JianminJ G Aaskov
Feb 12, 2008·Nature Structural & Molecular Biology·Shee-Mei LokMichael G Rossmann
Nov 13, 2008·Archives of Virology·Sérgio Oliveira De PaulaBenedito Antônio Lopes da Fonseca
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