Localization of corticotropin- and endorphin-related peptides in the intermediate lobe of the rat pituitary

Cell and Tissue Research
R MartinK H Voigt


The question is examined whether alpha-melanocyte stimulating hormone (alpha-MSH), adrenocorticotropic hormone (ACTH), met-enkephalin and beta-endorphin are detectable by enzyme immunocytochemistry in the cells of the intermediate lobe (PI) of the rat pituitary. By applying antibodies against alpha-MSH, ACTH and beta-endorphin on light microscopic sections, intense immunostaining was found in all PI-cells. At the ultrastructural level, after treatment of consecutive serial sections with these three antibodies the immunoreactivity was localized in the same secretory granules. No specific metenkephalin immunoreactivity could be detected in the cells of the intermediate lobe.


Mar 1, 1988·Cell and Tissue Research·N BäckT Laatikainen
Jan 1, 1980·Peptides·G A OlsonD H Coy
Dec 1, 1979·Neuroscience Letters·R MartinK H Voigt
Jan 1, 1981·Comparative Biochemistry and Physiology. C: Comparative Pharmacology·G J MartensA P van Overbeeke
Sep 20, 1996·Early Human Development·S J RothenbergL A Guzmán
Aug 14, 2013·Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft·Mattia PaninBruno Cozzi
Jan 1, 1985·Progress in Histochemistry and Cytochemistry·J A Litwin
Sep 1, 1985·The American Journal of Anatomy·F NakagawaS S Spicer
Jan 28, 1981·Molecular and Cellular Biochemistry·M Chrétien, N G Seidah

Related Concepts

Immune Sera
Melanocyte stimulating hormone
Pituitary Stalk
Rats, Laboratory

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