PMID: 3772075Nov 1, 1986Paper

Localization of eosinophil cationic protein, major basic protein, and eosinophil peroxidase in human eosinophils by immunoelectron microscopic technique

The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society
A EgestenI Olsson

Abstract

An immunoelectron microscopic technique using protein A-gold as a specific marker was used for precise intracellular localization of eosinophil granule proteins. Eosinophils from healthy individuals were isolated in metrizamide gradients. Eosinophil cationic protein (ECP) and eosinophil peroxidase (EPO) were clearly located in the matrix of the large crystalloid-containing granules. In addition, ECP was probably present in the small granules of eosinophils. Major basic protein (MBP) was present in the crystalloid structure of specific granules. This method can be applied in studies of eosinophil degranulation to trace the release of biological effector molecules.

Citations

Jan 1, 1990·Neurosurgical Review·W Müller, R Firsching
Jan 1, 1990·Agents and Actions·P Venge
Nov 3, 2010·Cell and Tissue Research·Revital ShamriLisa A Spencer
May 1, 1988·The Journal of Allergy and Clinical Immunology·G J GleichP M Vanhoutte
Apr 1, 1995·Critical Reviews in Oncology/hematology·D S Silberstein
Jul 1, 1989·Journal of the American Academy of Dermatology·K M LeifermanR K Winkelmann
Feb 5, 2003·Neuropathology : Official Journal of the Japanese Society of Neuropathology·Toshiko NagashimaKazuo Nagashima
Apr 18, 1991·The New England Journal of Medicine·P F Weller
Jan 25, 2003·International Ophthalmology Clinics·Ajay SrivastavaStefan D Trocmé
Jan 1, 1994·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A M DvorakT Ishizaka
Aug 1, 1994·Postgraduate Medical Journal·A J Wardlaw
Dec 1, 1988·The American Review of Respiratory Disease·P VengeC G Peterson
Oct 6, 2000·American Journal of Respiratory Cell and Molecular Biology·M KarawajczykP Venge
Mar 8, 2013·PloS One·Shun-lung FangMargaret Dah-Tsyr Chang
Dec 7, 2006·The American Journal of Pathology·Patricia C FulkersonMarc E Rothenberg
Jan 1, 1987·Histochemistry·M C LeeI Damjanov
Jun 13, 2003·Folia Microbiologica·P SímaK Sigler
Apr 1, 1991·Digestive Diseases and Sciences·T W McGovernG J Gleich
Sep 1, 2012·The Journal of Allergy and Clinical Immunology·James J LeeNancy A Lee
Dec 18, 2013·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·C Persson
Nov 1, 1994·Survey of Ophthalmology·S D Trocme, A J Aldave
Dec 19, 2013·PloS One·Ta-Jen HungMargaret Dah-Tsyr Chang
Jul 31, 2009·PloS One·Bente KötenJürgen Harder
Feb 2, 2015·Ultrasound in Medicine & Biology·Hedieh SaffariLeonard F Pease
May 26, 2012·Innate Immunity·Sandeep K GuptaThomas T Wheeler
Jul 14, 2004·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·C BezS Zielen
Jan 21, 2003·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·Rob R EversoleLeonard J Beuving
Sep 1, 1999·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·P VengeA Trulson
Sep 1, 2001·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A EgestenT Persson
Apr 29, 2009·Laboratory Investigation; a Journal of Technical Methods and Pathology·Rossana C N MeloPeter F Weller

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