Localization of epidermal-type fatty acid binding protein in alveolar macrophages and some alveolar type II epithelial cells in mouse lung

The Histochemical Journal
Yuji OwadaHisatake Kondo

Abstract

Almost all alveolar macrophages in the mouse lung were strongly immunoreactive for epidermal-type fatty acid binding protein. At the electron microscope level, the immunoreactive material was localized diffusely in the cytoplasm but not within the nucleus. A certain number of alveolar type II epithelial cells were also immunoreactive for the protein with variable immunointensity, while a substantial number of the type II cells were immunonegative. No immunoreactive interstitial fibroblasts were encountered. Based on the present findings, possible roles of epidermal-type fatty acid binding protein in the host-defence mechanism played by alveolar macrophages are suggested.

Citations

Jan 10, 2006·Journal of Molecular Histology·Mohammad Reza NouraniHisatake Kondo
Mar 8, 2008·The Tohoku Journal of Experimental Medicine·Yuji Owada
Apr 30, 2013·American Journal of Physiology. Lung Cellular and Molecular Physiology·Fabienne GallyRebecca E Oberley-Deegan
Apr 26, 2008·Annual Review of Nutrition·Judith Storch, Betina Corsico
Nov 18, 2006·Molecular and Cellular Biochemistry·Soha Abdelkawi AbdelwahabHisatake Kondo
Sep 22, 2010·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Julia HollerVeronika Grau
Jan 30, 2015·American Journal of Physiology. Endocrinology and Metabolism·Kimitaka ShibueNobuya Inagaki
Feb 22, 2018·Histochemistry and Cell Biology·Yasuhiko BandoOsamu Amano
Dec 24, 2010·American Journal of Respiratory Cell and Molecular Biology·Elisa GhelfiSule Cataltepe
Jan 27, 2019·Molecular Neurobiology·Ariful IslamYuji Owada
Jan 6, 2021·Histochemistry and Cell Biology·Yasuhiko BandoOsamu Amano
Feb 20, 2021·Anatomical Science International·Yui Yamamoto, Yuji Owada
Jul 14, 2010·Neuroscience Research·Nadezhda B BonevaTetsumori Yamashima

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.