Localization of fat depots and cardiovascular risk

Lipids in Health and Disease
Olga GruzdevaOlga Barbarash

Abstract

Despite the existing preventative and therapeutic measures, cardiovascular diseases remain the main cause of temporary disability, long-term disability, and mortality. Obesity is a major risk factor for cardiovascular diseases and their complications. However, not all fat depots have the same inflammatory, paracrine, and metabolic activities. In addition, recent studies have indicated that the accumulation of visceral fat, rather than subcutaneous fat, is associated with increased cardiometabolic risk. However, there is also evidence that increasing the area of visceral fat can help protect against lipotoxicity. This review aims to discuss the contemporary literature regarding the characteristics of the visceral, epicardial, and perivascular fat depots, as well as their associations with cardiovascular disease.

References

Dec 24, 1997·Diabetes Care·P J AndersonJ A Critchley
Jun 28, 2002·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Matthias LöhnArya M Sharma
Nov 24, 2004·Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology·Domenico CorradiCesare Bordi
Sep 28, 2005·Nature Clinical Practice. Cardiovascular Medicine·Gianluca IacobellisArya M Sharma
Nov 15, 2006·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·Andrea FrontiniSaverio Cinti
Jun 8, 2007·The New England Journal of Medicine·Earl S FordSimon Capewell
Aug 11, 2007·Arteriosclerosis, Thrombosis, and Vascular Biology·Anna Kotronen, Hannele Yki-Järvinen
Aug 23, 2008·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·S ErogluH Muderrisoglu
Jan 3, 2009·Clinical Science·Hanrui ZhangCuihua Zhang
Jan 6, 2009·Circulation Research·Tapan K ChatterjeeNeal L Weintraub
Jan 14, 2009·International Journal of Obesity : Journal of the International Association for the Study of Obesity·C L SchlettU Hoffmann
Feb 7, 2009·Diabetes & Metabolism·J Capeau
May 8, 2009·Metabolic Syndrome and Related Disorders·Masoud PezeshkianGhader Shahmohammadi
May 23, 2009·Journal of the American College of Cardiology·Carl J LavieHector O Ventura
Jul 14, 2009·Nursing Standard·Margaret Ashwell
Jul 14, 2010·Circulation·Nancy T ArtinianUNKNOWN American Heart Association Prevention Committee of the Council on Cardiovascular Nursing
Jul 28, 2010·The Journal of Biological Chemistry·Pedro Da SilvaFrédéric Gressent
Oct 26, 2011·Diabetic Medicine : a Journal of the British Diabetic Association·A M SironiA Gastaldelli
Dec 14, 2011·Circulation·Kathryn A Britton, Caroline S Fox
Jan 26, 2012·American Journal of Physiology. Endocrinology and Metabolism·Alain VeilleuxAndré Tchernof
Feb 16, 2012·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Michaela KozakovaUNKNOWN RISC Investigators
Aug 14, 2012·Cell Metabolism·A Christine Könner, Jens C Brüning
Sep 6, 2012·Circulation·Jean-Pierre Després
Apr 30, 2013·Nature Cell Biology·Matthias RosenwaldChristian Wolfrum
Jun 14, 2014·Arteriosclerosis, Thrombosis, and Vascular Biology·Abdullah OmarNeal L Weintraub
Aug 26, 2014·Annual Review of Pharmacology and Toxicology·Alexander Pfeifer, Linda S Hoffmann
Oct 26, 2014·Reviews in Endocrine & Metabolic Disorders·Nora Klöting, Matthias Blüher
Jan 28, 2015·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Paula BrauerUNKNOWN Canadian Task Force on Preventive Health Care

❮ Previous
Next ❯

Citations

Aug 2, 2019·The Journal of Clinical Hypertension·Tomasz MiazgowskiBartosz Miazgowski
Oct 10, 2019·Archives of Physiology and Biochemistry·Maxim Yu SinitskyAnastasia V Ponasenko
Jul 16, 2020·Menopause : the Journal of the North American Menopause Society·Julie J Lee, Chrisandra L Shufelt
Sep 18, 2020·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Abigail E SalineroKristen L Zuloaga
Aug 19, 2020·Cardiovascular Diabetology·Vera H W de Wit-VerheggenTineke van de Weijer
Aug 8, 2020·Klinicheskaia laboratornaia diagnostika·Yu A Dyleva, O V Gruzdeva
Aug 28, 2020·Menopause : the Journal of the North American Menopause Society·Julie J Lee, Chrisandra L Shufelt
May 21, 2019·Journal of Cellular Physiology·Daniele FerraraFederico Carbone
Dec 19, 2019·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·Patrick J OwenTimo Rantalainen
Feb 8, 2020·Journal of the American College of Cardiology·Jeffrey I MechanickW Timothy Garvey
Feb 10, 2021·International Journal of Obesity : Journal of the International Association for the Study of Obesity·Yu-Hsuan ChangShiow-Ching Shun
Mar 16, 2021·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Vicente J CogolloRaul J Rosenthal
Apr 6, 2021·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·Monica BignottoMassimo Zuin
Oct 5, 2020·Journal of the Academy of Nutrition and Dietetics·Moriah P BellissimoJessica A Alvarez
Aug 11, 2020·Cardiology in Review·Beth Hillary MottelWilliam H Frishman
Jul 6, 2021·Journal of the American Heart Association·Emily S LauJennifer E Ho
Jul 22, 2021·AJR. American Journal of Roentgenology·Jessica H PorembkaCecelia Brewington

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

Related Papers

Diabetic Medicine : a Journal of the British Diabetic Association
A M SironiA Gastaldelli
Wiener medizinische Wochenschrift
Carmen GelsingerChristoph F Ebenbichler
Clínica e investigación en arteriosclerosis : publicación oficial de la Sociedad Española de Arteriosclerosis
Vicente Lahera
© 2022 Meta ULC. All rights reserved