PMID: 7547467Jun 1, 1995Paper

Localization of Pbx1 transcripts in developing rat embryos

Mechanisms of Development
V J RobertsC Murre

Abstract

Recently, a new family of homeodomain proteins has emerged, that includes extradenticle, ceh-20, Pbx1, Pbx2 and Pbx3. The Pbx family has been shown to modulate the biological activities of the Hox proteins. We demonstrate here by in situ hybridization that Pbx1 transcripts are present in many embryonic tissues. Highest levels of Pbx1 expression in the developing embryo, from 12 to 20 days post coitum, are found in neuronal tissues, including brain, spinal cord and ganglia. In addition, Pbx1 transcripts are also detectable in the gut, lung, olfactory epithelium and kidney. The expression pattern of Pbx1 overlaps with that of many of the Hox gene products and is consistent with them acting in parallel to regulate common target genes.

References

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Citations

Nov 28, 2006·Bioinformatics·Ian B JefferyDesmond G Higgins
Jun 15, 2013·Cellular and Molecular Life Sciences : CMLS·Cédric Francius, Frédéric Clotman
Nov 13, 1998·Proceedings of the National Academy of Sciences of the United States of America·M R HoughI D Dubé
Mar 18, 2010·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Sarah E Coy, Anne-Gaëlle Borycki
Jun 15, 2013·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Franck Ladam, Charles G Sagerström
Aug 14, 2013·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Dorothea Schulte, Dale Frank
Aug 16, 2005·Stem Cells·Philip H SchwartzHenry Klassen
Jul 4, 2013·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Adi Zohar-StoopelAdi Salzberg
Nov 8, 2001·DNA Sequence : the Journal of DNA Sequencing and Mapping·A A PedersenB K Michelsen
Dec 25, 2007·Developmental Biology·Catherine A RottkampStephen O'Gorman
Feb 19, 2000·Developmental Dynamics : an Official Publication of the American Association of Anatomists·N VlachakisC G Sagerström
Mar 1, 1996·Mechanisms of Development·S SteinM Kessel

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