Localization of prostaglandin on the plasmalemma of rabbit sperm

The Journal of Experimental Zoology
W BartoszewiczM Gordon


Prostaglandin and prostaglandin receptors were localized on unwashed ejaculate rabbit sperm utilizing ferritin conjugated antibody to prostaglandin. Reaction was obtained over the acrosomal portion of the plasma membrane, with a greater aggregation over the apex of the head. The remainder of the head plasmalemma and flagellum showed no deposits of of reaction product. The reaction did not occur if the sperm were washed prior to incubation with the labelled antisera. However enhanced binding of ferritin was demonstrated if washed sperm were pre-incubated in PGE1. No reaction was seen in similar studies with human sperm.


Jan 25, 1974·Prostaglandins·J K DineenI D Smith
Jul 27, 1970·Biochemical and Biophysical Research Communications·E R Casillas, D D Hoskins
Feb 1, 1972·Proceedings of the National Academy of Sciences of the United States of America·F A Kuehl, J L Humes
Jul 1, 1973·The Journal of Experimental Zoology·M Gordon
Jul 1, 1973·Prostaglandins·A E Wakeling, K T Kirton
May 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·B R Olsen, D J Prockop
May 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·G C KooM P Lardis
Jul 1, 1972·Prostaglandins·R M ZusmanH R Behrman
Nov 1, 1973·Biology of Reproduction·G Oliphant, B G Brackett
Jan 1, 1974·Journal of Reproduction and Fertility·M GordonW Bartoszewicz
Mar 1, 1974·The Journal of Cell Biology·J K Koehler, W D Perkins
Feb 1, 1971·Journal of Reproduction and Fertility·R A VaidyaK Johnson
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Related Concepts

Establishment and Maintenance of Localization
Prostaglandin Receptor
Binding Sites, Antibody
Immune Sera
Receptors, Drug
Gamma globulin
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