PMID: 18208775Jan 23, 2008Paper

Localization of sentinel node in squamous cell carcinoma of the penis. Initial experience

Revista española de medicina nuclear
S RubíA Gelabert-Mas

Abstract

To assess the validity of radioguided sentinel node biopsy in squamous cell penile carcinoma. Fifteen patients were studied. The first 5 patients were included in a group for validation of the technique, in which a standard inguinal lymphadenectomy was performed after the procedures described below. The remaining 10 patients were included in the technique application group. The day before surgery, lymphoscintigraphy was performed on all patients. During the operation, radioguided biopsy to locate the sentinel node was done. Methylene blue dye was injected shortly before surgery in 10 patients. All patients were followed for an average of 32 months. In the validation group, lymphoscintigraphy revealed inguinal drainage in 5/5 patients. Unilateral metastases were detected in 3/5 patients. No metastatic nodes were detected among the nodes removed during inguinal lymphadenectomy. In the application group, lymphoscintigraphy showed inguinal drainage in 9/10 patients. Nineteen nodes were removed, none of which showed tumour involvement. During the follow-up period, no disease progression or recurrence were observed in either patient group. Radioguided localization and biopsy of the sentinel nodes can avoid unnecessary lymphadenectomi...Continue Reading

References

Dec 22, 2004·Journal of Surgical Oncology·Bin K KroonOmgo E Nieweg
Apr 14, 2005·European Urology·Bin K KroonOmgo E Nieweg

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.