Localized genital bullous pemphigoid

Clinical and Experimental Dermatology
S J MounseyC B Bunker

Abstract

Genital bullous pemphigoid (GBP) is a rare localized subset of bullous pemphigoid (BP). BP is characterized by autoantibodies against hemidesmosomes, which are involved in the structural integrity of the epidermis, and this results in subepidermal blistering. Typically, GBP affects women and children. We report an adult male who presented with a scrotal rash and blisters that developed into erosions. Only two previous cases in men have been reported. Immunofluoresence and histopathology confirmed the diagnosis of BP. The patient responded to mycophenolate mofetil and doxycycline.

References

Dec 13, 2005·International Journal of Dermatology·Julie T Tran, Diya F Mutasim
Oct 20, 2007·Journal of the American Academy of Dermatology·Orith Waisbourd-ZinmanAlex Zvulunov
Sep 16, 2008·Journal of Pediatric Urology·Moben MirzaJason M Wilson
Jun 6, 2014·International Journal of Dermatology·Igor Vázquez-OsorioJaime Toribio
Mar 14, 2017·Autoimmunity Reviews·Işın Sinem BağcıMiklós Sárdy

❮ Previous
Next ❯

Citations

Apr 4, 2019·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·Dimitra Kiritsi, Franziska Schauer
Dec 3, 2020·Actas dermo-sifiliográficas·F AlvesJ C Cardoso
Jun 30, 2021·Annales de dermatologie et de vénéréologie·E JolyJ Chanal
Dec 10, 2021·Journal of Cutaneous Pathology·Savannah M AlvaradoCampbell L Stewart

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of the American Academy of Dermatology
H C NousariG J Anhalt
The British Journal of Dermatology
E LaffitteL Borradori
International Journal of Dermatology
Igor Vázquez-OsorioJaime Toribio
The Medical Journal of Australia
H K MullerW G De Boer
© 2022 Meta ULC. All rights reserved