Localized ground glass opacities with multiple pulmonary small cysts in adult T-cell leukemia or lymphoma: an "alloy wheel" appearance

Journal of Thoracic Imaging
Aya SakashitaMasataka Uetani

Abstract

We herein report a case of adult T-cell leukemia or lymphoma showing multiple lung cysts within a localized ground glass opacity (GGO) on computed tomography scan. The patterns of multiple localized GGOs having multiple small cysts were varied, including a large air space in the center of the localized GGO with surrounding small cysts, a solid part in the center of the localized GGO with peripheral small cysts, and clustered small cysts. These findings were considered to simulate the appearance of an "alloy wheel." Some of the central large air spaces had thickened walls. On the basis of the histopathologic findings, the pathogenesis of multiple cyst formation was considered to be a combination of 2 main mechanisms as follows: a check valve mechanism due to stenosis or an obstruction by the tumor cells' infiltration along the bronchioles, traction bronchiolectasis and ectatic alveoli by fibrosis.

References

Nov 1, 1992·Radiology·G L WeisbrodF R Matzinger
May 1, 1973·Thorax·M R Chaudhuri
Sep 1, 1994·Journal of Computer Assisted Tomography·Y IchikawaN Hayabuchi
Jan 1, 1993·Radiographics : a Review Publication of the Radiological Society of North America, Inc·J E KuhlmanS S Siegelman
Jul 9, 1999·AJR. American Journal of Roentgenology·O HondaH Nakamura
Dec 10, 1999·AJR. American Journal of Roentgenology·M AkiraT Johkoh
Feb 21, 2004·AJR. American Journal of Roentgenology·Fumito OkadaHiromu Mori
Apr 9, 2005·Journal of Thoracic Imaging·Bradley S SabloffJeremy J Erasmus
Jan 24, 2008·Japanese Journal of Clinical Oncology·Noriko YamadaYoshihiro Matsuno

❮ Previous
Next ❯

Citations

Mar 15, 2016·Diagnostic Cytopathology·Jia QinConstantine A Axiotis
Jul 23, 2016·Revue des maladies respiratoires·A BeurtonF Chabot
Mar 9, 2017·Pathology Research International·Prajwal BodduAnjana Yeldandi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.