Localized Retinal Nerve Fiber Layer Defects in Red-free Photographs Versus En Face Structural Optical Coherence Tomography Images

Journal of Glaucoma
Jae Hoon JungYong Yeon Kim

Abstract

The purpose of this article is to compare the locations of localized retinal nerve fiber layer (RNFL) defects in red-free fundus photographs and optical coherence tomography (OCT) en face images. We performed a retrospective, comparative study on 46 eyes from 46 glaucoma patients with localized RNFL defects observed in red-free fundus photographs. En face structural images were obtained in the superficial and whole retinal layers using OCT and were overlaid on the corresponding red-free fundus photographs. The proximal/distal angular locations and angular width of each RNFL defect in red-free photos (red-free defects) and in en face structural images (en face defects) were compared. In the superficial retinal layer, there were no significant differences between red-free and en face defects on the proximal/distal angular location and angular width. In the whole retinal layer, the degree of the distal angular location of the en face defects was significantly larger than that of the red-free defects (71.85±18.26 vs. 70.87±17.90 degrees, P=0.003). The correlations of clinical variables with the differences in angular parameters between red-free and en face defects were not significant in the superficial retinal layer. The average R...Continue Reading

References

Dec 1, 1977·Archives of Ophthalmology·A SommerT George
Apr 15, 1991·American Journal of Ophthalmology·A Tuulonen, P J Airaksinen
Oct 1, 1983·American Journal of Ophthalmology·A SommerT George
Mar 8, 1997·Current Opinion in Ophthalmology·N Gupta, R N Weinreb
Mar 22, 2000·Acta Ophthalmologica Scandinavica·P TeesaluP J Airaksinen
Jan 29, 2002·American Journal of Ophthalmology·Mohamed A E SolimanMarc D De Smet
Jul 7, 2011·Investigative Ophthalmology & Visual Science·Xiang-Run HuangRobert W Knighton
Aug 24, 2012·Investigative Ophthalmology & Visual Science·Yugo KimuraNagahisa Yoshimura
Aug 12, 2014·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Tae-Eun LeeChungkwon Yoo
Oct 2, 2015·Investigative Ophthalmology & Visual Science·Donald C HoodToco Y P Chui
Mar 31, 2016·Developments in Ophthalmology·Philip J RosenfeldGiovanni Gregori

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Citations

Jul 14, 2020·Progress in Retinal and Eye Research·Gala BeykinJeffrey L Goldberg
Jan 11, 2021·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Alexander ChenIng-Chou Lai

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