Localizing Broca's area for transcranial magnetic stimulation: Comparison of surface distance measurements and stereotaxic positioning

Brain Stimulation
Nora WeiduschatAlexander Thiel

Abstract

Precise placement of transcranial magnetic stimulation (TMS) coils over target regions is crucial for correct interpretation of TMS effects. Modern frameless stereotaxic systems yield high accuracy, but require extensive equipment and cannot be used in every setting, for example, during functional imaging sessions. The aim of this study was the development of a method for TMS-coil placement based on individual imaging data without the need for external tracking devices. We compared coil positioning over Broca's area using an advanced stereotaxic navigation system with placement according to the surface distance measurements (SDM) method. By using the SDM-method, 3-dimensional renderings adapted from individual T1-weighted magnetic resonance imaging (MRI) data were created to identify Broca's area and Broca's homologue, respectively, and to define anatomic landmarks on the skin's surface. Distances between these landmarks were used to localize the real target on the individual's head. The mean Euclidean distance between surface positions as determined with the two methods was 8.31 mm and the mean difference of estimated virtual electric field intensity at the target point was 7.37 V/m corresponding to 4.01% of maximum field stre...Continue Reading

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Citations

May 12, 2011·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Caroline PaquetteAlexander Thiel
Mar 1, 2016·Restorative Neurology and Neuroscience·Edward P Washabaugh, Chandramouli Krishnan
Mar 5, 2015·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Alexander ThielUNKNOWN NORTHSTAR study group
Dec 18, 2010·Stroke; a Journal of Cerebral Circulation·Nora WeiduschatWolf Dieter Heiss
Feb 19, 2021·European Stroke Journal·Anna ZumbansenUNKNOWN NORTHSTAR-study group

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