PMID: 10456657Aug 24, 1999Paper

Locally advanced breast cancer in Saudi Arabia: high frequency of stage III in a young population

Medical Oncology
Adnan A EzzatR K Stuart

Abstract

In the Kingdom of Saudi Arabia (KSA), breast cancer constitutes 18% of all cancers in Saudi women. Whilst locally advanced breast cancer disease is unusual in Western countries, it constitutes more than 40% of all non-metastatic breast cancer in KSA. The relative frequency of locally advanced disease among our breast cancer population and the lack of a uniform consensus in the literature about its optimal management have prompted this retrospective analysis of the medical records of patients with Stage III breast cancer patients seen at King Faisal Specialist Hospital and Research Center between 1981 and 1991. In all, 315 patients were identified. Their median age +/- SD was 46 +/- 11.6 years which is distinctly different from the 60-65 years median age in industrial Western nations. Most patients were younger than 50 years (64%) and premenopausal (62%). Patients were approximately equally divided between Stage IIIA and Stage III B. Patients received multimodality treatment, including surgery, adjuvant chemotherapy, tamoxifen, and adjuvant radiotherapy. Sixty-one patients were excluded from survival analysis as they were considered lost to follow-up. Of the remaining 254 patients, 73 (29%) were alive and disease free, and 18 pa...Continue Reading

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Citations

Mar 17, 2004·The Breast : Official Journal of the European Society of Mastology·M Al-MoundhriC Grant
Nov 10, 2000·Breast Cancer Research and Treatment·A A EzzatS M Bazarbashi
Jan 7, 2011·Journal of Oncology·Arafat TfayliAli Shamseddine
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