Locally advanced breast implant-associated anaplastic large-cell lymphoma: a case report of successful treatment with radiation and chemotherapy

Frontiers in Oncology
Christopher F EstesChristopher Lominska

Abstract

The development of breast implant-associated anaplastic large-cell lymphoma (ALCL) is a rare phenomenon. A typical presentation is an effusion associated with a breast implant. Less commonly, disease can be more advanced locoregionally or distantly. The optimal treatment schema is a topic of debate: localized ALCL can potentially be cured with implant removal alone, while other cases in the literature, including those that are more advanced, have been treated with varying combinations of surgery, chemotherapy, and external beam radiotherapy. This is a case report of breast implant ALCL with pathologically proven lymph node involvement, the fifth such patient reported. Our patient experienced a favorable outcome with radiation therapy and chemotherapy.

References

Jun 1, 1997·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·M VaseiZ Amirghofran
Aug 1, 1997·Plastic and Reconstructive Surgery·J A Keech, B J Creech
Aug 15, 1998·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·J O Armitage, D D Weisenburger
Nov 6, 2008·JAMA : the Journal of the American Medical Association·Daphne de JongFlora E van Leeuwen
Mar 26, 2009·Plastic and Reconstructive Surgery·Loren LipworthJoseph K McLaughlin
Mar 2, 2011·Plastic and Reconstructive Surgery·Benjamin KimSoeren Mattke
Jul 22, 2011·Plastic and Reconstructive Surgery·Matthew J CartyEphraim P Hochberg
May 23, 2012·The American Journal of Surgical Pathology·Tariq N AladilyRoberto N Miranda
Jun 15, 2013·Current Hematologic Malignancy Reports·Philip A Thompson, H Miles Prince
Dec 11, 2013·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Roberto N MirandaL Jeffrey Medeiros

❮ Previous
Next ❯

Citations

Sep 4, 2015·Journal of Autoimmunity·Mojca BizjakYehuda Shoenfeld
Aug 19, 2016·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·Guillermo Ramos-GallardoCesar Torres-Rivero
Dec 2, 2017·The American Journal of Surgical Pathology·Maria C Ferrufino-SchmidtRoberto N Miranda
Mar 1, 2019·Plastic and Reconstructive Surgery·Meredith S CollinsMark W Clemens
Jun 8, 2019·Journal of Medical Imaging and Radiation Oncology·Ruvini Thashila GunawardanaDonna B Taylor
Apr 11, 2018·Aesthetic Surgery Journal·Sanam LoghaviRoberto N Miranda
Jan 2, 2021·Clinical Lymphoma, Myeloma & Leukemia·Shaikha AlotaibiMahmoud Aljurf
Aug 1, 2020·Clinical Oncology : a Journal of the Royal College of Radiologists·M CoA Kwong
Jan 20, 2021·Yeungnam University Journal of Medicine·Jun-Ho Lee

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsy

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.