Locally advanced cervical cancer: A study of 5-year outcomes

Indian Journal of Cancer
Supriya ChopraS K Shrivastava

Abstract

Cervical cancer is the second most common cancer among Indian women. This present retrospective study was conducted to report patient outcomes with locally advanced cervical cancer treated in the year 2010. Case records of cervical cancer patients registered from January 1, 2010, to December 31, 2010 were retrieved. A total of 1200 patients were registered, of which 583 received either definitive or adjuvant radiotherapy (RT). Of these, 345 patients who received complete treatment at our hospital were included for outcome analysis. Descriptive statistics were used to summarize patient- and treatment-related variables, and Kaplan-Meier analysis was performed for survival analysis. The median age was 56 years (range: 33-90). Squamous carcinoma was the most common histology (91.4%) and the majority were FIGO Stage III (45.4%). Median follow-up of the cohort was 44 months (1-85 months). The 5-year disease-free survival (DFS) across stages was 50%. Most important predictor of DFS was FIGO staging (Stage II vs. Stage III: 62% vs. 45%) and use of concurrent chemoradiotherapy (CTRT) l (RT vs. CTRT: 32% vs. 57%, respectively). Patients aged >70 years had a significantly poor DFS at 5 years; however, did not have any effect on survival. ...Continue Reading

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Citations

Jun 6, 2019·Journal of Global Oncology·Supriya ChopraShyam Kishore Shrivastava
Oct 21, 2020·Indian Journal of Cancer·Rohan SalunkheShyam Kishore Shrivastava
Aug 21, 2021·Frontiers in Cell and Developmental Biology·Yue FengYunyan Zhang

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