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LOCAS--a low coverage assembly tool for resequencing projects

PloS One

Aug 23, 2011

Juliane D KleinDaniel H Huson

Abstract

Next Generation Sequencing (NGS) is a frequently applied approach to detect sequence variations between highly related genomes. Recent large-scale re-sequencing studies as the Human 1000 Genomes Project utilize NGS data of low coverage to afford sequencing of hundreds of individuals. He...read more

Mentioned in this Paper

Genome
DNA Resequencing
Sequencing
Massively-Parallel Sequencing
Sequence Determinations, DNA
Arabidopsis thaliana extract
Chromosomes
Suffix brand of benzoylprop-ethyl
Genome Sequencing
Single Nucleotide Polymorphism
137
Paper Details
References
  • References32
  • Citations12
1234
  • References32
  • Citations12
12

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LOCAS--a low coverage assembly tool for resequencing projects

PloS One

Aug 23, 2011

Juliane D KleinDaniel H Huson

PMID: 21858125

DOI: 10.1371/journal.pone.0023455

Abstract

Next Generation Sequencing (NGS) is a frequently applied approach to detect sequence variations between highly related genomes. Recent large-scale re-sequencing studies as the Human 1000 Genomes Project utilize NGS data of low coverage to afford sequencing of hundreds of individuals. He...read more

Mentioned in this Paper

Genome
DNA Resequencing
Sequencing
Massively-Parallel Sequencing
Sequence Determinations, DNA
Arabidopsis thaliana extract
Chromosomes
Suffix brand of benzoylprop-ethyl
Genome Sequencing
Single Nucleotide Polymorphism
137

Feeds With Similar Papers

Structural Biology: Biophysics

Structural Biology: Biophysics describes the study of structural biology using various biophysical techiniques such as imaging, computational modeling, etc. Discover the latest research on structrual biology here.

Related Papers

Bioinformatics

Efficient construction of an assembly string graph using the FM-index

BioinformaticsJune 10, 2010
Jared T Simpson, Richard Durbin
Genome Research

Stampy: a statistical algorithm for sensitive and fast mapping of Illumina sequence reads

Genome ResearchOctober 29, 2010
Gerton Lunter, Martin Goodson
Paper Details
References
  • References32
  • Citations12
1234
  • References32
  • Citations12
12

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