Location of focal vasospasm provoked by ergonovine maleate within coronary arteries in patients with vasospastic angina pectoris

The American Journal of Cardiology
Tomomi KoizumiPeter J Fitzgerald

Abstract

This study examined whether coronary focal vasospasm occurs in a nonuniform distribution within the coronary tree and whether a longitudinal plaque distribution pattern is present in patients with vasospastic angina using 3-dimensional intravascular ultrasound analysis. Of 121 patients with clinically suspected angina without fixed stenosis in the coronary arteries, vasospasm was provoked in 82 patients with 92 lesions (42 focal, 50 diffuse) by intravenous ergonovine maleate injection. Most focal vasospasms occurred in the proximal third of the coronary arteries (proximal 28, mid 8, distal 6, p <0.01), corresponding to the historical high-risk zones for acute coronary occlusion. More plaque burden also existed in the proximal third of the coronary arteries in patients with focal vasospasm.

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Citations

Jul 31, 2010·Circulation Journal : Official Journal of the Japanese Circulation Society·UNKNOWN JCS Joint Working Group
Sep 24, 2010·Case Reports in Medicine·Sarfraz Ahmed NazirCharles Ilsley
Feb 17, 2015·Case Reports in Medicine·Min LiYujie Liu
Oct 16, 2010·Cardiovascular Therapeutics·George V Moukarbel, Larry A Weinrauch
Oct 3, 2014·Circulation Journal : Official Journal of the Japanese Circulation Society·UNKNOWN JCS Joint Working Group
Jul 5, 2019·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Rocco Antonio MontoneFilippo Crea
Oct 28, 2020·Cardiovascular Intervention and Therapeutics·Satoru SuzukiKenichi Tsujita

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