Location-weighted CTP analysis predicts early motor improvement in stroke: a preliminary study.

Neurology
S PayabvashM H Lev

Abstract

To develop multivariate models for prediction of early motor deficit improvement in acute stroke patients with focal extremity paresis, using admission clinical and imaging data. Eighty consecutive patients with motor deficit due to first-ever unilateral stroke underwent CT perfusion (CTP) within 9 hours of symptom onset. Limb paresis was prospectively assessed using admission and discharge NIH Stroke Scale (NIHSS) scoring. CTP scans were coregistered to the MNI-152 brain space and subsegmented to 146 pairs of cortical/subcortical regions based on preset atlases. Stepwise multivariate binary logistic regressions were performed to determine independent clinical and imaging predictors of paresis improvement. The rates of early motor deficit improvement were 18/49 (37%), 15/42 (36%), 8/25 (32%), and 7/23 (30%) for the right arm, right leg, left arm, and left leg, respectively. Admission NIHSS was the only independent clinical predictor of early limb motor deficit improvement. Relative CTP values of the inferior frontal lobe white matter, lower insular cortex, superior temporal gyrus, retrolenticular portion of internal capsule, postcentral gyrus, precuneus parietal gyri, putamen, and caudate nuclei were also independent predictors...Continue Reading

References

Jan 1, 1995·European Neurology·E KuneschH J Freund
Dec 28, 2000·Acta Neurologica Scandinavica·H FeysW De Weerdt
Apr 5, 2003·Stroke; a Journal of Cerebral Circulation·Anna C ZemkeSteven C Cramer
Mar 24, 2004·Cognition·Nina F DronkersJeri J Jaeger
Nov 16, 2005·Brain Injury : [BI]·D G NairJ A S Kelso
Nov 24, 2006·Stroke; a Journal of Cerebral Circulation·Nina M MenezesA Gregory Sorensen
Jun 23, 2007·Journal of Cognitive Neuroscience·Daniel Y KimbergMyrna F Schwartz
May 10, 2008·AJNR. American Journal of Neuroradiology·F Torres-MozquedaR G González
May 30, 2009·Annals of Neurology·Randolph S MarshallJohn W Krakauer
Oct 14, 2010·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Bastian ChengGötz Thomalla
Nov 3, 2010·Lancet Neurology·Cathy Stinear
Apr 19, 2011·PM & R : the Journal of Injury, Function, and Rehabilitation·Hua WangM Elizabeth Sandel
Jun 7, 2011·Neuroimaging Clinics of North America·Angelos A KonstasMichael H Lev

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Citations

Jul 5, 2016·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Seyedmehdi PayabvashAlexander M McKinney
Sep 7, 2016·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Seyedmehdi PayabvashAdnan I Qureshi
Feb 7, 2017·The British Journal of Radiology·Seyedmehdi PayabvashAdnan I Qureshi
Mar 28, 2017·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Mark R EthertonOna Wu
Feb 17, 2018·AJNR. American Journal of Neuroradiology·Z ChenM Lou
Mar 7, 2014·Stroke; a Journal of Cerebral Circulation·Wolf-Dieter Heiss, Chelsea S Kidwell
Sep 13, 2015·The International Journal of Cardiovascular Imaging·Joseph Yeen Young, Pamela Whitney Schaefer
Oct 17, 2020·AJNR. American Journal of Neuroradiology·S M SeyedsaadatD F Kallmes
May 1, 2021·AJNR. American Journal of Neuroradiology·S M SeyedsaadatJ D Schaafsma
Aug 26, 2021·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Huacong LiuJunqi Chen

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