Loneliness predicts postprandial ghrelin and hunger in women

Hormones and Behavior
Lisa M JaremkaJanice K Kiecolt-Glaser

Abstract

Loneliness is strongly linked to poor health. Recent research suggests that appetite dysregulation provides one potential pathway through which loneliness and other forms of social disconnection influence health. Obesity may alter the link between loneliness and appetite-relevant hormones, one unexplored possibility. We examined the relationships between loneliness and both postmeal ghrelin and hunger, and tested whether these links differed for people with a higher versus lower body mass index (BMI; kg/m(2)). During this double-blind randomized crossover study, women (N=42) ate a high saturated fat meal at the beginning of one full-day visit and a high oleic sunflower oil meal at the beginning of the other. Loneliness was assessed once with a commonly used loneliness questionnaire. Ghrelin was sampled before the meal and postmeal at 2 and 7h. Self-reported hunger was measured before the meal, immediately postmeal, and then 2, 4, and 7h later. Lonelier women had larger postprandial ghrelin and hunger increases compared with less lonely women, but only among participants with a lower BMI. Loneliness and postprandial ghrelin and hunger were unrelated among participants with a higher BMI. These effects were consistent across both ...Continue Reading

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Citations

Aug 8, 2018·Journal of Interpersonal Violence·Ruth Pinedo GonzálezMyriam de la Iglesia Gutiérrez
Aug 11, 2018·Current Psychiatry Reports·Lisa M JaremkaNaoyuki Sunami
Nov 14, 2020·International Journal of Environmental Research and Public Health·Shang-Yu YangPin-Hsuan Lin
Jul 24, 2021·Current Obesity Reports·Leslie J Heinberg, Kristine Steffen

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