Long acting β2-adrenocepter agonists are not associated with atrial arrhythmias after pulmonary resection

Journal of Cardiothoracic Surgery
Keiji YamanashiCheng-Long Huang

Abstract

Long-acting β2-adrenoceptor agonists have been shown to increase the risk of atrial arrhythmias in patients with stable chronic obstructive pulmonary disease. The aim of this study was to investigate whether perioperative long-acting β2-adrenoceptor agonists treatment would increase the risk of postoperative atrial arrhythmias after lung cancer surgery in chronic obstructive pulmonary disease patients. We retrospectively analyzed 174 consecutive chronic obstructive pulmonary disease patients with non-small-cell lung cancer who underwent lobectomy or segmentectomy. The subjects were divided into those with or without perioperative long-acting β2-adrenoceptor agonists treatment. Postoperative cardiopulmonary complications were compared between the two groups. There were no statistically significant differences between the perioperative long-acting β2-adrenoceptor agonists treatment group and the control group in the incidence of postoperative atrial arrhythmias (P = 0.629). In 134 propensity-score-matched pairs, including variables such as age, gender, comorbidities, smoking history, operation procedure, lung-cancer staging, and respiratory function, there were no significant differences between the two groups in the incidence of...Continue Reading

References

Jul 1, 1990·The Annals of Thoracic Surgery·A J RitchieJ R Gibbons
Jan 6, 1999·The Annals of Thoracic Surgery·J J CurtisR A Schmaltz
Sep 28, 2001·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·O RenaG Maggi
Feb 23, 2007·The New England Journal of Medicine·Peter M A CalverleyUNKNOWN TORCH investigators
Feb 7, 2009·The European Respiratory Journal·R P YoungG D Gamble
May 2, 2009·The European Respiratory Journal·P J Barnes, B R Celli
Apr 19, 2011·Respiratory Medicine·Denis E O'DonnellUNKNOWN INABLE 1 study group
Aug 11, 2012·American Journal of Respiratory and Critical Care Medicine·Jørgen VestboRoberto Rodriguez-Roisin
Dec 18, 2013·Interactive Cardiovascular and Thoracic Surgery·Jelena IvanovicAndrew J E Seely
Oct 17, 2015·Surgery Today·Takekazu IwataIchiro Yoshino

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Methods Mentioned

BETA
surgical resection
X-ray

Software Mentioned

SPSS
R

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