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Long-lasting dopamine receptor up-regulation in amphetamine-treated rats following amphetamine neurotoxicity

Pharmacology, Biochemistry, and Behavior

Dec 1, 1991

J Z FieldsJ H Gordon

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Abstract

Amphetamine (A) (9.2 mg/kg, IP), in combination with iprindole (I) (10.0 mg/kg, IP), caused long-lasting dopamine (DA) depletions in striatum (-49%, 4 weeks) but not in nucleus accumbens following one A/I injection. Striatal DA had recovered by 4 months. DA receptors (DAr) were up-regul...read more

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Nucleus Accumbens
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Stereotyped Behavior
5
1
Paper Details
References
  • References20
  • Citations5
12
  • References20
  • Citations5
1

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Long-lasting dopamine receptor up-regulation in amphetamine-treated rats following amphetamine neurotoxicity

Pharmacology, Biochemistry, and Behavior

Dec 1, 1991

J Z FieldsJ H Gordon

PMID: 1816575

DOI: 10.1016/0091-3057(91)90101-7

Abstract

Amphetamine (A) (9.2 mg/kg, IP), in combination with iprindole (I) (10.0 mg/kg, IP), caused long-lasting dopamine (DA) depletions in striatum (-49%, 4 weeks) but not in nucleus accumbens following one A/I injection. Striatal DA had recovered by 4 months. DA receptors (DAr) were up-regul...read more

Mentioned in this Paper

Cyclic Peptides
Oxydess
Schizophrenia
August Rats
Lentiform Nucleus Structure
Cyclo(leucylglycine), (S)-isomer
Dopamine Receptor
Nucleus Accumbens
Intropin
Stereotyped Behavior
5
1

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Paper Details
References
  • References20
  • Citations5
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  • References20
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Download from

Publisher
PubMed
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