Long-lasting successful cerebral response with sorafenib in advanced renal cell carcinoma.

Journal of Neuro-oncology
Francesca ValcamonicoGiovanni Marini

Abstract

We report the case of a 75-year old woman who received sorafenib (Nexavar), Bayer Pharmaceuticals Corporation, West Haven, CT) for a CNS relapse of clear cell renal cell carcinoma. After four months of sorafenib treatment, a brain magnetic resonance imaging showed 95%-volumetric regression of cerebral metastasis. To the best of our knowledge, this is the first almost complete resolution of brain metastases in renal cell carcinoma treated with sorafenib that has been described.

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Oct 16, 2009·Expert Review of Anticancer Therapy·Axel S MerseburgerMarkus A Kuczyk
Nov 14, 2015·CNS Drugs·Michael P GabayJohn L Villano
Aug 19, 2011·Journal of Clinical Immunology·Oliver CrespoWilliam H Robinson
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Sep 24, 2009·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Shuiying HuSharyn D Baker
Jan 28, 2010·Molecular Cancer Therapeutics·Jurjen S LagasAlfred H Schinkel

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