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Long noncoding RNA high expression in hepatocellular carcinoma facilitates tumor growth through enhancer of zeste homolog 2 in humans

Hepatology : Official Journal of the American Association for the Study of Liver Diseases

Jul 20, 2011

Fu YangShuhan Sun

Abstract

In recent years, long noncoding RNAs (lncRNAs) have been shown to have critical regulatory roles in cancer biology. However, the contributions of lncRNAs to hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) remain largely unknown. Differentially expressed lncRNAs between HB...read more

Mentioned in this Paper

Gene Expression Regulation, Neoplastic
RNA, Untranslated
Liver Carcinoma
HEIH gene
Recurrent Malignant Neoplasm
Hepatitis B Virus
Polycomb Repressive Complex 2
EZH2 protein, human
Repressor Molecules
Hepatocellular Carcinoma of the Mouse
142
1
Paper Details
References
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  • Citations211
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Long noncoding RNA high expression in hepatocellular carcinoma facilitates tumor growth through enhancer of zeste homolog 2 in humans

Hepatology : Official Journal of the American Association for the Study of Liver Diseases

Jul 20, 2011

Fu YangShuhan Sun

PMID: 21769904

DOI: 10.1002/hep.24563

Abstract

In recent years, long noncoding RNAs (lncRNAs) have been shown to have critical regulatory roles in cancer biology. However, the contributions of lncRNAs to hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) remain largely unknown. Differentially expressed lncRNAs between HB...read more

Mentioned in this Paper

Gene Expression Regulation, Neoplastic
RNA, Untranslated
Liver Carcinoma
HEIH gene
Recurrent Malignant Neoplasm
Hepatitis B Virus
Polycomb Repressive Complex 2
EZH2 protein, human
Repressor Molecules
Hepatocellular Carcinoma of the Mouse
142
1

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Hepatitis B Virus

Hepatitis B virus is the most common cause of hepatitis worldwide and is associated with acute, fulminant, and chronic hepatitis, as well as liver cirrhosis and hepatocellular carcinoma. Here is the latest research.

PRC2 And Gene Silencing (Keystone)

Polycomb repressive complex 2 (PRC2) is a class of polycomb-group proteins. It can mediate methylation of histone H3 on lysine 27, thereby silencing gene transcription. This feed focuses on the latest research relating to Eva Nogales' talk on "Structural Insights into the Regulation of the Gene Silencer PRC2".

Related Papers

Paper Details
References
  • References32
  • Citations211
1234
  • References32
  • Citations211
12345...
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