Long-range synchronization of oscillatory light responses in the cat retina and lateral geniculate nucleus

Nature
S Neuenschwander, W Singer

Abstract

Visual responses in the retina and the lateral geniculate nucleus (LGN) exhibit oscillatory patterning within a broad range of frequencies. Oscillatory activity is often associated with the synchronization of spatially distributed responses. Here we demonstrate, with simultaneous multi-electrode recordings from the retina and the LGN, that stationary and moving light stimuli evoke in retinal ganglion cells oscillatory responses in the frequency range of 61 to 114 Hz that become synchronized over distances larger than 20 degrees of visual angle across the nasal and temporal halves of the retina. This temporal patterning of retinal responses is transmitted reliably by LGN neurons, such that stimuli crossing the vertical meridian evoke synchronous responses in the LGNs of both hemispheres. The oscillatory responses are not phase-locked to the stimulus onset, indicating that synchronization results from horizontal interactions in the retina. The occurrence of synchronization depends on global stimulus properties such as size and continuity, suggesting that temporal correlation among responses of spatially segregated ganglion cells can be exploited to convey information relevant for perceptual grouping.

References

Jun 1, 1979·The Journal of Physiology·L Peichl, H Wässle
May 12, 1978·Experimental Brain Research·D W Arnett
Mar 1, 1976·Journal of Neurophysiology·J K Stevens, G L Gerstein
Nov 1, 1992·Journal of Neurophysiology·G M Ghose, R D Freeman
Apr 1, 1991·Physiological Reviews·H Wässle, B B Boycott
Feb 1, 1989·Trends in Neurosciences·D N Mastronarde
Dec 1, 1987·Journal of the Optical Society of America. A, Optics and Image Science·J G Robson, J B Troy
Mar 1, 1967·Vision Research·M Laufer, M Verzeano
Sep 1, 1967·Journal of Neurophysiology·R W Rodieck
Aug 1, 1981·The Journal of Physiology·D Arnett, T E Spraker
Jan 1, 1995·Annual Review of Neuroscience·W Singer, C M Gray
Aug 1, 1995·Microscopy Research and Technique·J E Cook, D L Becker
Aug 1, 1963·The Journal of Physiology·R W DOTY, D S KIMURA
Apr 1, 1964·The Journal of Physiology·P O BISHOPW O WILLIAMS

❮ Previous
Next ❯

Citations

Sep 24, 1999·Journal of Neuroscience Research·C Hölscher
Aug 10, 2006·Biological cybernetics·Greg J StephensGarrett T Kenyon
Nov 6, 2008·Biological cybernetics·Kilian Koepsell, Friedrich T Sommer
Jan 13, 2009·Cognitive Processing·Walter G Sannita
Aug 2, 2008·Journal of Computational Neuroscience·Adrien Wohrer, Pierre Kornprobst
Sep 25, 2010·Journal of Computational Neuroscience·Wen-Zhong LiuPei-Ji Liang
Aug 12, 2009·Journal of Biological Physics·Walter G Sannita
Jun 30, 2009·Cognitive Neurodynamics·Wolf Singer
Jun 1, 2005·Brain Research. Brain Research Reviews·David LaBerge
Sep 29, 2001·Trends in Neurosciences·E G Jones
Oct 3, 1999·Neuroscience Letters·S Shumikhina, S Molotchnikoff
Mar 22, 2002·Neuroscience·S W HughesV Crunelli
Mar 29, 2003·Neural Networks : the Official Journal of the International Neural Network Society·Ralf Der, Darragh Smyth
Aug 1, 1996·Current Opinion in Neurobiology·R C Reid, J M Alonso
Aug 1, 1997·Current Opinion in Neurobiology·R Ritz, T J Sejnowski
May 14, 1999·Current Opinion in Neurobiology·W Singer
Feb 13, 2001·Trends in Cognitive Sciences·A K. Engel, W Singer
Mar 23, 2000·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·W G Sannita
Dec 21, 2007·Visual Neuroscience·Susmita ChatterjeeNorberto M Grzywacz
Jul 19, 2008·Visual Neuroscience·Daniel K FreemanChristopher L Passaglia
Jul 5, 2005·Nature Neuroscience·Hiroshi IshikaneMasao Tachibana
Sep 29, 1998·The European Journal of Neuroscience·G Rager, W Singer
Apr 13, 2000·The European Journal of Neuroscience·S Molotchnikoff, S Shumikhina
May 20, 2011·Journal of Neural Engineering·Daniel K FreemanShelley I Fried
Apr 11, 2008·Cerebral Cortex·Shan YuDanko Nikolic
Jun 20, 1998·Proceedings. Biological Sciences·G T Kenyon, D W Marshak
Dec 17, 1998·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·W Singer
Mar 11, 2003·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Vincenzo CrunelliStephen R Williams
Mar 11, 2003·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Edward G Jones
Mar 11, 2003·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Sergio NeuenschwanderWolf Singer
Mar 11, 2004·Journal of Integrative Neuroscience·Soh HidakaEi-Ichi Miyachi
Jun 30, 2011·Journal of Integrative Neuroscience·Mahdi Jalili, Maria G Knyazeva
Apr 30, 2009·Annual Review of Neuroscience·Pascal Fries
Mar 6, 2007·Annual Review of Neuroscience·G D Field, E J Chichilnisky

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.