Long-term accumulation and microdistribution of uranium in the bone and marrow of beagle dog

International Journal of Radiation Biology
J D Arruda-NetoV R Vanin

Abstract

The accumulation and microdistribution of uranium in the bone and marrow of Beagle dogs were determined by both neutron activation and neutron-fission analysis. The experiment started immediately after the weaning period, lasting till maturity. Two animal groups were fed daily with uranyl nitrate at concentrations of 20 and 100 microg g(-1) food. Of the two measuring techniques, uranium accumulated along the marrow as much as in the bone, contrary to the results obtained with single, acute doses. The role played by this finding for the evaluation of radiobiological long-term risks is discussed. It was demonstrated, by means of a biokinetical approach, that the long-term accumulation of uranium in bone and marrow could be described by a piling up of single dose daily incorporation.

References

Jul 1, 1991·The British Journal of Radiology·R B RichardsonD L Henshaw
Sep 1, 1990·International Journal of Cell Cloning·B I Lord
May 1, 1987·Health Physics·C W MaysM E Wrenn

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Citations

Jan 15, 2008·Radiation Protection Dosimetry·G R PradoT E Rodrigues
Mar 25, 2011·Journal of Toxicology and Environmental Health. Part a·M A McDiarmidK S Squibb
Aug 27, 2013·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·G RodriguesE M Fontes
Dec 24, 2014·Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry·Grégory ChatelainDaniel Meyer
Jan 1, 2006·Journal of Analytical Atomic Spectrometry·David J BellisPatrick J Parsons
May 15, 2021·Biological Reviews of the Cambridge Philosophical Society·Gabriella J SpatolaTimothy A Mousseau

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