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Long-term balancing selection in LAD1 maintains a missense trans-species polymorphism in humans, chimpanzees and bonobos

bioRxiv

Jun 27, 2014

João Carlos TeixeiraAida M. Andres

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Abstract

Balancing selection maintains advantageous genetic and phenotypic diversity in populations. When selection acts for long evolutionary periods selected polymorphisms may survive species splits and segregate in present-day populations of different species. Here, we investigate the role of...read more

Mentioned in this Paper

Gene Expression
Gene Polymorphism
Species
Genetic Polymorphism
Pan troglodytes
Population Group
Dermoepidermal Junction
Leukocyte Adhesion Deficiency Type 1
LAD1 gene
Lad1 protein, mouse
10
13
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  • Long-term balancing selection in LAD1 maintains a missense trans-species polymorphism in humans, chimpanzees and bonobos

    bioRxiv

    Jun 27, 2014

    João Carlos TeixeiraAida M. Andres

    PMID: 990006684

    DOI: 10.1101/006684

    Abstract

    Balancing selection maintains advantageous genetic and phenotypic diversity in populations. When selection acts for long evolutionary periods selected polymorphisms may survive species splits and segregate in present-day populations of different species. Here, we investigate the role of...read more

    Mentioned in this Paper

    Gene Expression
    Gene Polymorphism
    Species
    Genetic Polymorphism
    Pan troglodytes
    10
    13

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