journal cover

Long-term balancing selection in LAD1 maintains a missense trans-species polymorphism in humans, chimpanzees and bonobos

bioRxiv

Jun 27, 2014

João C TeixeiraAida M Andrés

Abstract

Balancing selection maintains advantageous genetic and phenotypic diversity in populations. When selection acts for long evolutionary periods selected polymorphisms may survive species splits and segregate in present-day populations of different species. Here, we investigate the role of...read more

Mentioned in this Paper

LAD1 gene
Lad1 protein, mouse
Dermoepidermal Junction
Anchoring Activity
Species
Locus
Genetic Polymorphism
Pan paniscus
VCHSK TRSNP ENNVG L
Autoantigens
10
13
Paper Details
References
  • References
  • Citations
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations
  • quote and clock

    No citations available

    This paper may not have been cited yet.

Similar Papers Found In These Feeds

Cytoskeletal Dynamics

The cytoskeleton is a dynamic system that is involved in numerous cellular functions. The dynamic cytoskeleton has a close relationship with formation and trafficking of vesicles, spindle localization, cell compartmentation and more. Here is the latest research on cytoskeletal dynamics.

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.

BioRxiv Preprints

BioRxiv is the preprint server for biology, operated by Cold Spring Harbor Laboratory. Here are the latest biology preprint articles from bioRxiv.

Intermediate Filaments

Intermediate filaments provide mechanical support for cells and tissues. Discover the latest research on intermediate filaments here.

Cytoskeletal Collection

The cytoskeleton is a dynamic network of interlinking protein filaments that extends from the plasma membrane to the nucleus. Here is the latest research.

Immune Tolerance

Immune tolerance happens when the immune system is not responsive to a substance or organism and does not elicit an immune response. This is a normal physiological response for some antigens, especially when detecting self from non-self. This has been a potential area of therapy for some disorders. Here is the latest research on immune tolerance.

Comparative Sequencing

Inter/Intra-Species: Comparative Sequencing describes the sequencing techniques that compare between and within species genomes. Discover the latest research on comparative sequencing of inter/intra-species here.

© 2020 Meta ULC. All rights reserved

Long-term balancing selection in LAD1 maintains a missense trans-species polymorphism in humans, chimpanzees and bonobos

bioRxiv

Jun 27, 2014

João C TeixeiraAida M Andrés

PMID: 990006684

DOI: 10.1101/006684

Abstract

Balancing selection maintains advantageous genetic and phenotypic diversity in populations. When selection acts for long evolutionary periods selected polymorphisms may survive species splits and segregate in present-day populations of different species. Here, we investigate the role of...read more

Mentioned in this Paper

LAD1 gene
Lad1 protein, mouse
Dermoepidermal Junction
Anchoring Activity
Species
Locus
Genetic Polymorphism
Pan paniscus
VCHSK TRSNP ENNVG L
Autoantigens
10
13

Similar Papers Found In These Feeds

Related Papers

Paper Details
References
  • References
  • Citations
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations
  • quote and clock

    No citations available

    This paper may not have been cited yet.
/papers/long-term-balancing-selection-in-lad1-maintains-a/990006684