Long-Term Body Composition Changes in Women Following Roux-en-Y Gastric Bypass Surgery

JPEN. Journal of Parenteral and Enteral Nutrition
Abigail J ColeCarrie P Earthman

Abstract

Although most individuals experience successful weight loss following Roux-en-Y gastric bypass (RYGB), weight regain is a concern, the composition of which is not well documented. Our aim was to evaluate changes in body composition and handgrip strength as a measure of functional status in participants from a previous 1-year post-RYGB longitudinal study who had undergone RYGB approximately 9 years prior. Five women from an original larger cohort were monitored pre-RYGB and 1.5 months, 6 months, 1 year, and 9 years post-RYGB. Body composition was assessed at all time points using dual energy x-ray absorptiometry and multiple dilution. Handgrip strength was measured using a digital isokinetic hand dynamometer (Takei Scientific Instruments, Ltd, Tokyo, Japan). Mean time to final follow-up was 8.7 years. Lean soft tissue (LST) loss over the ~9-year period was on average 11.9 ± 5.6 kg. Compared with 1-year post-RYGB, 9-year LST was 4.4 ± 3.0 kg lower ( P = .03). Fat-free mass decreased over the 9-year period by 12.6 ± 5.8 kg. Mean fat mass (FM) decreased from 75.4 ± 22.6 kg pre-RYGB to 35.5 ± 21.5 kg 1 year post-RYGB but then trended toward an increase of 8.6 ± 7.0 kg between 1 year and 9 years post-RYGB ( P = .053). Loss of LST was...Continue Reading

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Citations

Aug 2, 2018·Nature Reviews. Endocrinology·John A Batsis, Dennis T Villareal
May 27, 2020·Current Obesity Reports·Julie M ParrottMary O'Kane
May 18, 2020·Obesity Surgery·Malou A H NuijtenMaria T E Hopman
Feb 15, 2018·JPEN. Journal of Parenteral and Enteral Nutrition·Ajay Kumar JainBruce M Wolfe
Oct 25, 2020·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Neda HaghighatMasoud Amini

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Methods Mentioned

BETA
gastric bypass

Software Mentioned

Lunar iDXA
BOD POD
SAS
GraphPad Prism
GraphPad

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