Long-term clinical and pathologic response of Barrett's esophagus after antireflux surgery

American Journal of Surgery
James M O'RiordanJohn V Reynolds

Abstract

The impact of antireflux surgery on outcome in Barrett's esophagus, in particular its effect on both the regression of metaplasia and the progression of metaplasia through dysplasia to adenocarcinoma, remains unclear. This long-term follow-up study evaluated clinical, endoscopic, histopathologic, and physiologic parameters in patients with Barrett's esophagus who underwent antireflux surgery in a specialist unit. Between 1985 and 2001, 58 patients with Barrett's esophagus (49 long-segment and 9 short-segment) underwent a Rossetti-Nissen fundoplication, 32 via open procedure and 26 laparoscopically. Symptomatic follow-up with a detailed questionnaire was available in 58 (100%) and follow-up endoscopy and histology in 57 (98%) patients, and 41 patients (71%) underwent preoperative and postoperative 24-hour pH monitoring. At a median follow-up of 59 months, 52 patients (90%) had excellent symptom control, whereas 6 patients (10%) had significant recurrent symptoms and were on regular proton pump inhibitor medication. Seventeen of 41 patients having preoperative and postoperative pH monitoring (41%) had a persistent increase of acid reflux above normal. Thirty-five percent (20 of 57) of patients showed either partial or complete re...Continue Reading

Citations

Nov 18, 2006·Surgical Endoscopy·L BierthoJ Weerts
Aug 28, 2009·Surgical Endoscopy·Melina C VassiliouRichard I Rothstein
Jan 4, 2013·Surgery Today·Tatsuya MiyazakiHiroyuki Kuwano
Jul 11, 2007·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Giovanni ZaninottoErmanno Ancona
Sep 12, 2007·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Hugo BonattiRonald A Hinder
Sep 18, 2007·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Narayanasamy RaviJohn V Reynolds
Aug 19, 2008·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·S E AttwoodT Lind
Nov 17, 2011·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Giovanni ZaninottoMassimo Rugge
May 7, 2011·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Tuuli M E KauttuJarmo A Salo
Apr 29, 2009·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Filippo TosatoMarcello Bezzi
Aug 11, 2010·World Journal of Gastroenterology : WJG·Eelco B Wassenaar, Brant K Oelschlager
Aug 6, 2014·International Journal of Surgery·L Max AlmondHugh Barr
Mar 6, 2007·World Journal of Surgery·David I WatsonDamian J Hussey
May 10, 2006·ANZ Journal of Surgery·Jeremyd Hayden, Glyng Jamieson
May 9, 2014·World Journal of Surgery·Marco E Allaix, Marco G Patti
May 30, 2015·Gastroenterology Clinics of North America·Christian G Peyre, Thomas J Watson
Jan 20, 2005·The Medical Clinics of North America·Mitchell S Cappell
Aug 18, 2005·Thoracic Surgery Clinics·Carl-Christian A Jackson, Steven R DeMeester
Jan 24, 2006·Seminars in Thoracic and Cardiovascular Surgery·Thomas W RiceJohn R Goldblum
Feb 24, 2016·British Journal of Hospital Medicine·Neel Sharma, Khek Yu Ho
Dec 13, 2006·The American Journal of Gastroenterology·J David HorwhatRoy K H Wong
Jan 22, 2010·The Cochrane Database of Systematic Reviews·Jonathan Re ReesRebecca C Fitzgerald
Jun 17, 2006·Advances in Anatomic Pathology·Robert M Genta
Feb 19, 2005·Journal of Clinical Gastroenterology·Herbert C Wolfsen
Dec 22, 2004·The Japanese Journal of Thoracic and Cardiovascular Surgery : Official Publication of the Japanese Association for Thoracic Surgery = Nihon Kyōbu Geka Gakkai Zasshi·Takashi OnoJun-ichi Ogawa
Sep 5, 2014·Digestive Diseases and Sciences·Theresa NguyenHashem B El-Serag
Oct 30, 2013·Gut·Rebecca C FitzgeraldUNKNOWN British Society of Gastroenterology
Apr 9, 2020·Annals of the New York Academy of Sciences·Luigi BonavinaRoger P Tatum
Oct 1, 2014·Annals of the New York Academy of Sciences·William H AllumBarbara M Zonderhuis
Jun 12, 2013·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Salvatore MaranoFilippo Tosato
Mar 27, 2020·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Pierre Allemann, Pierre Fournier
Sep 29, 2011·Annals of the New York Academy of Sciences·Paolo PariseGianmattia del Genio
Sep 29, 2011·Annals of the New York Academy of Sciences·Helen M ShieldsThomas G Schnell
Jan 4, 2020·Obesity Surgery·Franco SignoriniFederico Moser
Oct 9, 2020·Surgical Endoscopy·Colin P DunnJohn C Lipham
Feb 2, 2017·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Pawanindra LalAmarender Singh Puri
May 29, 2021·The Surgical Clinics of North America·Ekaterina Fedorova, Thomas J Watson
Mar 11, 2006·Annales de chirurgie·J-Y Mabrut, J Baulieux

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