Long-term clinical course of patients with isolated myocardial bridge

Circulation Journal : Official Journal of the Japanese Circulation Society
Sung-Soo KimJung Chaee Kang

Abstract

Myocardial bridge (MB) is regarded as a common benign lesion on coronary angiography (CAG). It is known to be harmless but may cause several cardiac events and recurrent hospitalization, so in the present study the long-term clinical course of patients with isolated MB and predictors of readmission were investigated. Total 684 patients (343 males, 60.5+/-11.2 years) with persistent chest pain without critical stenosis on CAG were enrolled. The patients were divided into 2 groups according to the presence of MB. Clinical follow-up was performed with respect to readmission after baseline CAG. At a mean follow-up of 37 months, 92 patients (13.3%) were re-admitted because of 79 recurrent chest pain refractory to medication (11.5%), 8 myocardial infarctions (1.2%), 1 life-threatening arrhythmia (0.1%) and 4 deaths (0.6%). There was a significant higher incidence of readmission in the MB group (P=0.038). In multivariate analysis, long MB (hazard ratio (HR) 2.780; 95% confidence interval (CI) 1.070-7.218, P=0.036) and spontaneous vasospasm in CAG (HR 2.335; 95%CI 1.055-5.171, P=0.037) were the predictors of readmission. Moreover, additional use of aspirin or statin decreased the readmission rate. This study suggests that MB on non-occ...Continue Reading

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Citations

Feb 2, 2011·Circulation Journal : Official Journal of the Japanese Circulation Society·Kazuhisa TakamuraJunichi Yamazaki
Apr 7, 2011·Circulation Journal : Official Journal of the Japanese Circulation Society·Yukio IshikawaToshiharu Ishii
Nov 12, 2010·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Kun TangRuming Lu
Sep 10, 2015·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Martin PoryoHashim Abdul-Khaliq
Dec 23, 2014·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Daniele RovaiMichele Coceani
Mar 6, 2012·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Emine BilenEngin Bozkurt
Oct 19, 2017·Journal of Forensic Sciences·Sorin HostiucMihaela Hostiuc
Dec 18, 2012·Arteriosclerosis, Thrombosis, and Vascular Biology·Yibo WangRutai Hui
Aug 7, 2019·Interactive Cardiovascular and Thoracic Surgery·Yuichiro KitadaHomare Okamura
May 18, 2020·Clinical Medicine : Journal of the Royal College of Physicians of London·Li ZhouHui Chen
Jul 4, 2017·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Mengmeng YuJiayin Zhang
Nov 9, 2017·Scientific Reports·Sorin HostiucIonuț Negoi

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