Long-term clinical outcomes of Ahmed valve implantation in patients with refractory glaucoma

PloS One
Chang Kyu LeeChan Yun Kim

Abstract

To evaluate the long-term efficacy of intraocular pressure (IOP) reduction and complications of Ahmed Glaucoma Valve (AGV) implantation in patients with refractory glaucoma. Retrospective study. The study involved 302 refractory glaucoma patients who underwent AGV implantation and had a minimum follow-up of 6 months between March 1995 and December 2013. An operation was defined as successful when (1) the postoperative IOP remained between 5 and 21 mmHg and was reduced 30% compared to the baseline IOP with or without medication, (2) there was no loss of light perception or vision-threatening severe complications, and (3) no additional filtering or aqueous drainage surgery was required. Clinical records were reviewed. IOP, anti-glaucoma medications, and complications. The mean follow-up period was 62.25 months (range, 6 to 190 months). The cumulative probability of success was 89% at 6 months, 81% at 1 year, 66% at 3 years, 44% at 10 years, and 26% at 15 years. IOP was reduced from a mean of 32.2 ± 10.5 mmHg to 18.6 ± 9.1 mmHg at 1 month, 15.2 ± 7.0 mmHg at 6 months, and 14.2 ± 3.5 mmHg at 15 years. Surgical failures were significantly increased when preoperative IOP was high, and when severe complications occurred after AGV impl...Continue Reading

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Citations

Jun 20, 2018·Journal of Glaucoma·Jessica Q H ChooPaul Chew
Aug 1, 2019·Cutaneous and Ocular Toxicology·Burak ErdemNimet Yesim Ercalik
Jan 3, 2020·Current Opinion in Ophthalmology·Rizwan MalikDeepak P Edward
Jul 3, 2020·Journal of Clinical Medicine·Chiara PosarelliMichele Figus
Jan 5, 2019·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·William E SponselMadeleine Puig
Feb 4, 2021·Journal of Glaucoma·Fernanda N SusannaRemo Susanna
May 13, 2021·Journal of Glaucoma·Veronique Promelle, Christopher J Lyons

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