Long-term cognitive follow-up of Parkinson's disease patients with impulse control disorders

Movement Disorders : Official Journal of the Movement Disorder Society
Chiara SiriGianni Pezzoli

Abstract

This study investigated cognitive functions in Parkinson's disease (PD) patients with impulse control disorders (ICDs) and aimed to identify possible predictors of behavioral outcome. In this longitudinal cohort study, 40 PD outpatients with ICDs and 40 without, were matched for sex, age at PD onset, age and disease duration at cognitive assessment. All patients had two neuropsychological assessments at least 2 years apart (mean, 3.5 years). Multivariate logistic regression analysis was performed to identify predictors of ICDs remission at follow-up. The PD patients with and without ICDs had overall comparable cognitive performance at baseline. When evaluating changes between baseline and follow-up, we found significant group × time interactions in several frontal lobe-related tests, with the ICDs group showing a less pronounced worsening over time. ICDs remission was associated with better performance at baseline in working memory-related tasks, such as digit span (odds ratio [OR] = 2.69 [95% confidence interval (CI), 1.09-6.66]) and attentive matrices (OR=1.19 [95%CI, 1.03-1.37]). ICDs remitters and non-remitters had no remarkable differences in baseline PD-related features and therapy management strategies (including the ext...Continue Reading

References

Nov 1, 1986·The Quarterly Journal of Experimental Psychology. A, Human Experimental Psychology·A BaddeleyH Spinnler
Mar 23, 2000·Journal of Neurology, Neurosurgery, and Psychiatry·G GiovannoniA J Lees
Mar 14, 2002·Journal of Experimental Child Psychology·Philip David Zelazo, Ulrich Müller
May 4, 2005·Trends in Cognitive Sciences·Kevin N Ochsner, James J Gross
Feb 14, 2007·Archives of Neurology·Valerie VoonMateusz Zurowski
May 31, 2007·Movement Disorders : Official Journal of the Movement Disorder Society·Javier PagonabarragaJaime Kulisevsky
Oct 27, 2007·Movement Disorders : Official Journal of the Movement Disorder Society·Eugenia MamikonyanDaniel Weintraub
Dec 22, 2007·Movement Disorders : Official Journal of the Movement Disorder Society·Bruno DuboisMurat Emre
Sep 4, 2009·Journal of Neurology·Chiara SiriAngelo Antonini
Oct 9, 2009·Brain : a Journal of Neurology·Caroline H Williams-GrayRoger A Barker
Mar 13, 2010·Parkinsonism & Related Disorders·Melis SohtaoğluEthem Erginöz
May 12, 2010·Archives of Neurology·Daniel WeintraubAnthony E Lang
Nov 12, 2010·Movement Disorders : Official Journal of the Movement Disorder Society·Claire L TomlinsonCarl E Clarke
Feb 22, 2011·Journal of Neurology, Neurosurgery, and Psychiatry·W G J ReidG M Halliday
Mar 4, 2011·Movement Disorders : Official Journal of the Movement Disorder Society·Carmine VitalePaolo Barone
Mar 19, 2011·Annals of Neurology·Valerie VoonMark Stacy
May 3, 2011·Biological Psychiatry·Roshan Cools, Mark D'Esposito
May 5, 2011·Brain Structure & Function·Roberto Cilia, Thilo van Eimeren
Jun 21, 2011·Journal of the Neurological Sciences·Asunción ÁvilaFrancesc Sastre
Oct 6, 2011·Movement Disorders : Official Journal of the Movement Disorder Society·Aleksandra KudlickaJohn V Hindle
Apr 26, 2012·Journal of Neurology·Michele Poletti, Ubaldo Bonuccelli
May 1, 2012·Neuroscience·J W Dalley, J P Roiser
Jun 13, 2012·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Marco MonacoGiovanni Augusto Carlesimo
Nov 20, 2012·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Anna Rita BentivoglioAntonio Daniele
Jan 4, 2013·Movement Disorders : Official Journal of the Movement Disorder Society·Jesse BastiaensMelissa J Nirenberg
Sep 7, 2013·Journal of Neuropsychology·Georg Dirnberger, Marjan Jahanshahi
Sep 27, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Philippa L RockRobert D Rogers
Oct 19, 2013·Frontiers in Psychology·Damien BreversXavier Noël
Nov 8, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Luke ClarkGui Xue
Jan 16, 2014·Parkinsonism & Related Disorders·Roberto CiliaGianni Pezzoli
Mar 1, 2014·Brain : a Journal of Neurology·Zheng YeJames B Rowe

❮ Previous
Next ❯

Citations

Oct 21, 2016·Journal of Neurology·Aristide MerolaLeonardo Lopiano
Mar 1, 2017·Neuroscience and Biobehavioral Reviews·Gabriella SantangeloPaolo Barone
Nov 9, 2017·Harvard Review of Psychiatry·R Ryan Darby, Bradford C Dickerson
Jul 5, 2018·Arquivos de neuro-psiquiatria·Antonio Pedro Vargas, Francisco Eduardo Costa Cardoso
Mar 8, 2018·Journal of Neural Transmission·Ana MarquesPierre-Olivier Fernagut
Nov 30, 2018·Rinshō shinkeigaku = Clinical neurology·Nozomu MatsudaYoshikazu Ugawa
Oct 20, 2019·Journal of Neurology·Aleksander H ErgaKenn Freddy Pedersen
Oct 29, 2017·Journal of Neurology, Neurosurgery, and Psychiatry·Lucia RicciardiMark Edwards
Jan 4, 2020·European Journal of Nuclear Medicine and Molecular Imaging·Juan Marín-LahozJaime Kulisevsky
Mar 21, 2017·Journal of Neurology, Neurosurgery, and Psychiatry·Angelo AntoniniPaolo Stanzione
Jun 26, 2015·Current Opinion in Neurology·Mateusz Zurowski, Jonathan Darcy O'Brien
Sep 28, 2017·Movement Disorders : Official Journal of the Movement Disorder Society·Alessandro TessitoreGioacchino Tedeschi
May 7, 2019·Frontiers in Neurology·Emilia M Gatto, Victoria Aldinio
Dec 18, 2019·Dementia & Neuropsychologia·Bruna de Assis Almeida, Amer Cavalheiro Hamdan
Dec 16, 2020·Brain : a Journal of Neurology·Garance M MeyerRoberto Cilia
Apr 10, 2020·Progress in Neuro-psychopharmacology & Biological Psychiatry·T Celeste NapierAmanda L Persons
Mar 14, 2019·Parkinsonism & Related Disorders·Ana MarquesUNKNOWN DIGPD study group
Jul 6, 2021·Parkinson's Disease·N Vila-ChãJ M Castro-Lopes

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Movement Disorders : Official Journal of the Movement Disorder Society
Roberto ErroPaolo Barone
Movement Disorders : Official Journal of the Movement Disorder Society
Michael SamuelAnthony E Lang
© 2022 Meta ULC. All rights reserved