Long-term effect of brief intervention in at-risk alcohol drinkers: a 9-year follow-up study

Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism
Odd Nilssen

Abstract

In 1986, 338 men and women attending a general population screening study were identified as at-risk alcohol drinkers and randomly assigned into three groups. Two groups received slightly different, brief interventions; a third group served as control. After 1 year there was a 50% reduction in alcohol intake in the intervention groups and a 20% increase in the control group. Controls then received advice to reduce their drinking. This study evaluates outcomes 9 years after these interventions. In a survey in the same city in 1995 (over 27 000 participants), 247 subjects (73.1%) from the 1986 study, were re-assessed. Serum gamma-glutamyltransferase (GGT) was examined and compared with values in 1986. A 'pseudo-control' group was established to compare 'treated' and 'untreated'. After 9 years, the original study groups displayed significant mean reduction in GGT. The reductions achieved in the three groups did not significantly differ from each other. However, the reductions were significantly greater than that in the 'pseudo-control' group. The impact of brief intervention appears to be long lasting. At 9 years follow-up, the at-risk drinkers displayed GGT values close to that of the background population.

References

Apr 1, 1992·Australian and New Zealand Journal of Medicine·J B Saunders, K Foulds
Aug 1, 1990·American Journal of Epidemiology·O NilssenT Brenn
Jun 22, 1985·British Medical Journal·P Anderson
Mar 1, 1993·Addiction·T H BienJ S Tonigan
Feb 1, 2002·Alcoholism, Clinical and Experimental Research·Michael F FlemingKristen Lawton Barry

❮ Previous
Next ❯

Citations

Dec 30, 2011·Population Health Management·Herbert T DavisMargaret J Gunter
Sep 29, 2011·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·Anders B Gottlieb HansenJanne Schurmann Tolstrup
Mar 31, 2012·Annals of Emergency Medicine·Gail D'OnofrioPatrick G O'Connor
Feb 7, 2009·La Presse médicale·Patrice CouzigouVictor De Ledinghen
Mar 11, 2010·The International Journal of Pharmacy Practice·Margaret C Watson, Alison Blenkinsopp
Oct 14, 2006·Journal of Clinical Nursing·Zena Hyman
Jul 21, 2006·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·Christopher Littlejohn
Jan 23, 2021·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·Mohsan SubhaniJoanne R Morling

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.