Long term effect of early intervention service on duration of untreated psychosis in youth and adult population in Hong Kong

Early Intervention in Psychiatry
Sherry K W ChanEric Yu Hai Chen

Abstract

The current study explored the effect of an early intervention (EI) service for psychosis in Hong Kong (EASY) on the reduction of the duration of untreated psychosis (DUP) at 10 years, in adolescent and adult patients. Data from three first-episode psychosis (FEP) studies conducted over 10 years using the same DUP assessment was analysed. FEP study 1 year before the EI service (2000) was used as a control, with those aged <25 comprising the youth psychosis control group and those aged over 25 comprising the adult psychosis control group. Data from the EASY service collected in 2010 constituted the youth psychosis EI group and data from an adult EI service collected from 2009 to 2011 constituted the adult psychosis EI group. DUP of EI and control groups was compared. The effect of the mode of onset and family history of psychosis on DUP was studied. DUP in the adult group was significantly reduced from median of 180 days to 93 days after 10 years (U = 12 906.50, P = 0.01), particularly in those with gradual onset and without family history. However, no significant change of DUP was found in the youth psychosis group. Results of the current study provide evidence that EI programmes with public awareness campaign can significantly...Continue Reading

References

Mar 1, 1992·Schizophrenia Research·H HäfnerW van der Heiden
Feb 6, 2004·Archives of General Psychiatry·Ingrid MelleThomas McGlashan
May 20, 2005·Social Psychiatry and Psychiatric Epidemiology·Eric Yu-Hai ChenWai-Nang Tang
Nov 2, 2006·The British Journal of Psychiatry : the Journal of Mental Science·Craig MorganUNKNOWN AESOP Study Group
Jun 13, 2009·The British Journal of General Practice : the Journal of the Royal College of General Practitioners·Helen LesterLynda Tait
Aug 18, 2010·Early Intervention in Psychiatry·Jennifer Y M TangEric Y H Chen
Oct 28, 2010·Early Intervention in Psychiatry·Cindy P-Y ChiuEric Y-H Chen
Jul 8, 2011·Nature·Pamela Y CollinsDan J Stein
Oct 6, 2011·The British Journal of Psychiatry : the Journal of Mental Science·Brynmor Lloyd-EvansSonia Johnson
Apr 27, 2013·Social Psychiatry and Psychiatric Epidemiology·Christy L M HuiEric Y H Chen
Sep 25, 2014·The British Journal of Psychiatry : the Journal of Mental Science·Matti PenttiläJouko Miettunen
Jan 8, 2015·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·Kelly K AndersonKwame J Mckenzie
Feb 7, 2015·The British Journal of Psychiatry : the Journal of Mental Science·Wing Chung ChangEric Yu Hai Chen

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.