Long-term effect of population screening for diabetes on cardiovascular morbidity, self-rated health, and health behavior

Annals of Family Medicine
Justin B Echouffo-TcheuguiSimon J Griffin

Abstract

There is limited trial evidence concerning the long-term effects of screening for type 2 diabetes on population morbidity. We examined the effect of a population-based diabetes screening program on cardiovascular morbidity, self-rated health, and health-related behaviors. We conducted a pragmatic, parallel-group, cluster-randomized controlled trial of diabetes screening (the ADDITION-Cambridge study) including 18,875 individuals aged 40 to 69 years at high risk of diabetes in 32 general practices in eastern England (27 practices randomly allocated to screening, 5 to no-screening for control). Of those eligible for screening, 466 (2.9%) were diagnosed with diabetes. Seven years after randomization, a random sample of patients was sent a postal questionnaire: 15% from the screening group (including diabetes screening visit attenders and non-attenders) and 40% from the no-screening control group. Self-reported cardiovascular morbidity, self-rated health (using the SF-8 Health Survey and EQ-5D instrument), and health behaviors were compared between trial groups using an intention-to-screen analysis. Of the 3,286 questionnaires mailed out, 1,995 (61%) were returned, with 1,945 included in the analysis (screening: 1,373; control: 572...Continue Reading

Citations

Aug 6, 2017·Journal of Racial and Ethnic Health Disparities·Shervin AssariJames E Aikens
Nov 1, 2018·Occupational Medicine·V BaliA P Legorreta
Jan 31, 2019·The Cochrane Database of Systematic Reviews·Lasse T KrogsbøllPeter C Gøtzsche
May 30, 2020·The Cochrane Database of Systematic Reviews·Nasheeta PeerSolange Durao
Aug 18, 2021·Endocrinology and Metabolism Clinics of North America·Daisy DuanJustin B Echouffo-Tcheugui
Aug 25, 2021·JAMA : the Journal of the American Medical Association·UNKNOWN US Preventive Services Task ForceJohn B Wong
Aug 25, 2021·JAMA : the Journal of the American Medical Association·Daniel E JonasRussell P Harris

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