Long-term effectiveness and cost-effectiveness of high versus low-to-moderate intensity resistance and endurance exercise interventions among cancer survivors

Journal of Cancer Survivorship : Research and Practice
Caroline S KampshoffLaurien M Buffart

Abstract

This study aimed to evaluate the long-term effectiveness and cost-effectiveness of high intensity (HI) versus low-to-moderate intensity (LMI) exercise on physical fitness, fatigue, and health-related quality of life (HRQoL) in cancer survivors. Two hundred seventy-seven cancer survivors participated in the Resistance and Endurance exercise After ChemoTherapy (REACT) study and were randomized to 12 weeks of HI (n = 139) or LMI exercise (n = 138) that had similar exercise types, durations, and frequencies, but different intensities. Measurements were performed at baseline (4-6 weeks after primary treatment), and 12 (i.e., short term) and 64 (i.e., longer term) weeks later. Outcomes included cardiorespiratory fitness, muscle strength, self-reported fatigue, HRQoL, quality-adjusted life years (QALYs) and societal costs. Linear mixed models were conducted to study (a) differences in effects between HI and LMI exercise at longer term, (b) within-group changes from short term to longer term, and (c) the cost-effectiveness from a societal perspective. At longer term, intervention effects on role (β = 5.9, 95% CI = 0.5; 11.3) and social functioning (β = 5.7, 95%CI = 1.7; 9.6) were larger for HI compared to those for LMI exercise. No sig...Continue Reading

References

Jul 1, 1990·Medical Decision Making : an International Journal of the Society for Medical Decision Making·W C Black
Apr 1, 1995·Journal of Psychosomatic Research·E M SmetsJ C De Haes
Dec 23, 1998·Journal of Hand Therapy : Official Journal of the American Society of Hand Therapists·R W Bohannon
May 8, 1995·Journal of Health Economics·M A KoopmanschapL van Roijen
Jun 25, 1999·Research Quarterly for Exercise and Sport·C J JonesW C Beam
May 6, 2004·Health Economics·Elisabeth FenwickAndrew Briggs
May 1, 2007·Archives of Physical Medicine and Rehabilitation·Ingrid C De BackerEric van Breda
Sep 2, 2008·Journal of Pain and Symptom Management·Michael A AndrykowskiPaul B Jacobsen
Jun 19, 2009·Medical Care·Kevin D Frick
Jul 1, 2009·BMJ : British Medical Journal·Jonathan A C SterneJames R Carpenter
Jul 25, 2009·Obesity·Melinda L IrwinLoretta DiPietro
Oct 23, 2009·International Journal of Technology Assessment in Health Care·Eija RoineTiina Saarto
Nov 18, 2009·Health Psychology : Official Journal of the Division of Health Psychology, American Psychological Association·Susan MichieSunjai Gupta
Jan 7, 2010·Journal of Cancer Survivorship : Research and Practice·Rebecca M SpeckKathryn H Schmitz
Jun 19, 2010·Medicine and Science in Sports and Exercise·Kathryn H SchmitzUNKNOWN American College of Sports Medicine
Jun 30, 2010·Circulation·Gary J BaladyUNKNOWN Interdisciplinary Council on Quality of Care and Outcomes Research
Jan 13, 2011·Statistics in Medicine·Ian R WhiteAngela M Wood
Nov 10, 2011·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Lynette L CraftKerry S Courneya
May 15, 2013·Medicine and Science in Sports and Exercise·Barbara StrasserCornelia M Ulrich
Jul 17, 2014·Journal of Cancer Survivorship : Research and Practice·C FosterP W Smith
Jul 29, 2015·EJC Supplements : EJC : Official Journal of EORTC, European Organization for Research and Treatment of Cancer ... [et Al.]·Neil K AaronsonLonneke V van de Poll-Franse
Apr 30, 2016·Medicine and Science in Sports and Exercise·Joeri KalterLaurien M Buffart

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Citations

Feb 27, 2019·Journal of Cancer Survivorship : Research and Practice·Hendrik MugeleMoritz Schumann
Jul 31, 2019·American Journal of Physical Medicine & Rehabilitation·Duc HaJames D Murphy
Sep 29, 2020·Journal of Cancer Survivorship : Research and Practice·Charlotte IJsbrandyRosella P M G Hermens
Apr 19, 2019·Breast Cancer Research and Treatment·Kamran Ahmad KhanJulie Bruce
Oct 17, 2019·CA: a Cancer Journal for Clinicians·Kathryn H SchmitzCharles E Matthews
Apr 25, 2020·Journal of Cancer Survivorship : Research and Practice·Cynthia C ForbesMiriam J Johnson
Nov 16, 2019·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Lionel PerrierBéatrice Fervers
Mar 27, 2019·Journal of Cancer Survivorship : Research and Practice·Sara MijwelYvonne Wengström
Oct 31, 2020·Health Services Research·Christopher R FrieseMilisa Manojlovich
Feb 25, 2021·Journal of Cancer Survivorship : Research and Practice·Barbara E Gubler-GutSabine Rohrmann
Jul 9, 2021·Cancer Reports·Melanie PotiaumpaiKathryn H Schmitz
Aug 14, 2021·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Isabelle DoréCatherine M Sabiston
Oct 30, 2021·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Alejandro Heredia-CiuróMarie Carmen Valenza

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Methods Mentioned

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