PMID: 15346055Sep 4, 2004Paper

Long-term effects of connective tissue cancer treatment

Clinical Orthopaedics and Related Research
H J MankinMark C Gebhardt

Abstract

In 1999, we began a study to assess the long-term effect of connective tissue cancer treatment on clinical, social, and psychologic aspects of the lives of surviving patients. A specially designed computer program generated an 85-item questionnaire, which was sent to more than 2000 patients with malignant bone and soft tissue neoplasms. Twelve hundred forty-four patients responded. The data were entered into a computer system and were correlated with the clinical information already contained in the system for the individual patients. Although there are many possible uses for these data, we chose to do a study comparing the lifestyle and physical and sociologic problems for 144 patients treated with chemotherapy and surgery for high-grade osteosarcoma against a control population consisting of 61 patients treated surgically for benign giant cell tumors of bone. The data show a remarkable degree of compensation on the part of the patients with the malignant tumors in terms of some problems but some significant differences particularly in physical status and functional limitations.

References

Feb 1, 1995·Archives of General Psychiatry·J S McDanielC B Nemeroff
Feb 1, 1994·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·C JenkinsonA Coulter
Mar 1, 1996·Clinical Orthopaedics and Related Research·H J MankinW W Tomford
Mar 1, 1996·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·D P MartinM F Swiontkowski
Mar 1, 1996·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·R EngelbergM F Swiontkowski
Aug 1, 1997·Pediatric Clinics of North America·P A Meyers, R Gorlick
Feb 12, 1999·Clinical Orthopaedics and Related Research·N J LindnerW Winkelmann
Oct 3, 1999·The Journal of Bone and Joint Surgery. American Volume·M F SwiontkowskiJ Agel
Apr 16, 2002·Clinical Orthopaedics and Related Research·Yasser RefaatHenry J Mankin
Apr 20, 2002·Clinical Orthopaedics and Related Research·Henry J Mankin

❮ Previous
Next ❯

Citations

Feb 2, 2006·Clinical Orthopaedics and Related Research·Poonam K PardasaneyHenry J Mankin

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Obstetrical & Gynecological Survey
A Fishman, E Paldi
Journal of the American Dietetic Association
A L Tobias, J B Gordon
Journal of the American Geriatrics Society
Takako Tsutsui, Naoko Muramatsu
© 2021 Meta ULC. All rights reserved