Long-term effects of heroin-assisted treatment in Germany

Addiction
U VertheinC Haasen

Abstract

Trials in Switzerland, the Netherlands and Spain have found that heroin-assisted treatment (HAT) as maintenance treatment for opioid-dependent patients reduces illicit drug use. A German trial also found diamorphine treatment to be superior to methadone treatment. The present study describes the association between 2 years of heroin treatment and improvements in health and social stabilization, as well as illicit drug use. A prospective cohort study design. A total of 515 patients were assigned to diamorphine treatment; 278 patients remained in the study treatment for the entire period of 24 months (54.8%). The results on physical (Opiate Treatment Index Health Symptoms Scale) and mental (Symptom Checklist 90-Revised Global Severity Index) health and illicit drug use (number of days with drug use within the last month-European Addiction Severity Index) were examined by repeated-measures analyses. Symptoms of physical (Pillai's trace = 0.837, df = 4, P < 0.001) and mental health (Pillai's trace = 0.450, df = 4, P < 0.001) improved during treatment. Street heroin use declined rapidly (Pillai's trace = 0.836, df = 4, P < 0.001), as did cocaine use (Pillai's trace = 0.280, df = 4, P < 0.001). HAT is associated with improvements in ...Continue Reading

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Citations

Sep 2, 2008·Journal of Urban Health : Bulletin of the New York Academy of Medicine·Eugenia Oviedo-JoekesMartin T Schechter
Apr 8, 2014·Journal of Controlled Release : Official Journal of the Controlled Release Society·Nowsheen GoonooDhanjay Jhurry
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Mar 8, 2011·Drug and Alcohol Review·Ambros A Uchtenhagen
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Jun 9, 2014·Substance Abuse Treatment, Prevention, and Policy·Eugenia Oviedo-JoekesMartin T Schechter
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