Long-term effects of immunization with recombinant lipoprotein outer surface protein a on serologic test for lyme disease

Clinical and Diagnostic Laboratory Immunology
Paul T FawcettVictoria Maduskuie

Abstract

Immunization with recombinant lipoprotein outer surface protein A vaccine is known to interfere with some serologic tests for Lyme disease. We tested sera from 152 vaccine recipients by using in-house and commercial Western blot assays and found that vaccination caused interference in up to 25% of recipients and can persist for over 6 years.

References

Oct 19, 1999·Journal of Clinical Microbiology·M E Aguero-RosenfeldG P Wormser
Jul 29, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·P J MolloyL H Sigal
Jan 4, 2001·Clinical and Diagnostic Laboratory Immunology·P T FawcettK M Gibney

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