PMID: 11912358Mar 26, 2002Paper

Long-term effects of simultaneous subconjunctival and subscleral mitomycin C application in repeat trabeculectomy

Journal of Glaucoma
Yi-an YouXiao-qin Ma

Abstract

To assess the efficacy and safety of simultaneous mitomycin C application under conjunctival and scleral flaps in patients with repeat trabeculectomy. A total of 44 patients (44 eyes) with previous failed filtering surgery were randomized to one of two groups. The both-flaps group comprised 22 patients (22 eyes) with trabeculectomy and intraoperative mitomycin C application under conjunctival and scleral flaps, whereas the subconjunctival group comprised 22 patients (22 eyes) with subconjunctival application of mitomycin C. Particular attention was paid to intraocular pressure, postoperative medications, visual acuity, filtering bleb appearance, and complications. The mean follow-up time was 38.18 +/- 12.48 months. The mean preoperative intraocular pressure decreased from 39.1 +/- 7.3 mm Hg to the postoperative level of 15.6 +/- 4.8 mm Hg in the both-flaps group (P = 0.014), and from 39.4 +/- 8.4 to 18.7 +/- 5.8 mm Hg in the subconjunctival group (P = 0.018). There was a statistically significant difference in intraocular pressure at all follow-up times, except at 1 week and 1 month postoperatively. Kaplan-Meier survival analysis showed there was no significant difference in total success rate (complete plus qualified success) ...Continue Reading

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Citations

Mar 23, 2013·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Yi-An YouSaijing Hu
Jun 6, 2007·International Ophthalmology·Ioannis KyprianouEammon O'Neill
Aug 14, 2009·American Journal of Ophthalmology·Steven J GeddeUNKNOWN Tube Versus Trabeculectomy Study Group
Aug 15, 2013·International Ophthalmology·Yadollah EslamiSasan Moghimi
Apr 7, 2016·Journal of Ophthalmic & Vision Research·Shahin YazdaniElham Ghahari
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Mar 29, 2012·Clinical & Experimental Ophthalmology·Carpi OlaliAnthony J King
Feb 27, 2017·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Ronan ConlonIqbal Ike K Ahmed
Aug 10, 2005·American Journal of Ophthalmology·Steven J GeddeUNKNOWN Tube Versus Trabeculectomy Study Group
Apr 17, 2004·International Ophthalmology Clinics·Sean-Paul A AtreidesAdam C Reynolds
Nov 29, 2005·Eye·G Rebolleda, F J Muñoz-Negrete
Jan 20, 2017·The British Journal of Ophthalmology·Mohammad PakravanParto Pakravan
Feb 1, 2017·The British Journal of Ophthalmology·Ignacio Rodriguez-UnaAnthony J King
Dec 2, 2011·Korean Journal of Ophthalmology : KJO·Ali Bulent Cankaya, Ufuk Elgin
Jun 17, 2006·Journal of Glaucoma·Rajiv Khandekarl, Rajiv Zutshi
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Aug 19, 2007·Journal of Glaucoma·Nitin Anand, Seema Arora
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Feb 26, 2009·Current Opinion in Ophthalmology·Quang H Nguyen
Oct 1, 2019·Journal of Current Glaucoma Practice·Maria Ev GuimarãesFábio N Kanadani
Nov 7, 2006·American Journal of Ophthalmology·Steven J GeddeDonald L Budenz
Jan 17, 2012·American Journal of Ophthalmology·Steven J GeddeUNKNOWN Tube versus Trabeculectomy Study Group

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