PMID: 3511493Jan 1, 1986

Long-term endocrinologic changes in subjects practicing the Transcendental Meditation and TM-Sidhi program

Psychosomatic Medicine
O R WernerR A Chalmers


The Transcendental Meditation (TM) and a more advanced program, the TM-Sidhi program, have been reported to produce a number of acute and long-term metabolic and electrophysiologic changes. To investigate the possibility that the practice of these techniques may be associated with long-term endocrinologic changes, we prospectively evaluated 11 male subjects before and over a 3-year period after starting the TM-Sidhi program. A progressive decrease in serum TSH, growth hormone, and prolactin levels occurred over the 3 years while no consistent change in cortisol, T4, or T3 levels was observed. These results suggest that the long-term practice of the TM and TM-Sidhi program may have effects on neuroendocrine function. Further studies using 24-hr monitoring with frequent blood sampling will, however, be needed to fully assess the significance of the simultaneous decline of the anterior pituitary hormones with maintenance of levels of hormones from peripheral endocrine glands.


Apr 5, 2003·The American Psychologist·Teresa E SeemanMelvin Seeman
Jun 6, 2013·Molecular Neurobiology·Vishal JindalRitwik Das
Jan 1, 1994·Psychoneuroendocrinology·C Kirschbaum, D H Hellhammer
Feb 5, 2010·Complementary Therapies in Clinical Practice·Rose H MatousekJens Pruessner
Aug 26, 2006·Epilepsy & Behavior : E&B·Ephraim Philip Lansky, Erik K St Louis
Mar 29, 2014·Frontiers in Psychology·Andrew B Newberg
Jun 6, 2014·Evidence-based Complementary and Alternative Medicine : ECAM·Sridip Chatterjee, Samiran Mondal
May 8, 2013·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Monika RaniNeena Srivastava
Aug 17, 2019·Stress : the International Journal on the Biology of Stress·Bonnie Klimes-DouganKelvin O Lim
Jan 27, 2021·Medicina·Robert Keith Wallace, Ted Wallace

Related Concepts

Hydrocortisone, (9 beta,10 alpha,11 alpha)-Isomer
Relaxation Techniques
Recombinant Growth Hormone

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Neural Activity: Imaging

Imaging of neural activity in vivo has developed rapidly recently with the advancement of fluorescence microscopy, including new applications using miniaturized microscopes (miniscopes). This feed follows the progress in this growing field.

The Tendon Seed Network

Tendons are rich in the extracellular matrix and are abundant throughout the body providing essential roles including structure and mobility. The transcriptome of tendons is being compiled to understand the micro-anatomical functioning of tendons. Discover the latest research pertaining to the Tendon Seed Network here.

Myocardial Stunning

Myocardial stunning is a mechanical dysfunction that persists after reperfusion of previously ischemic tissue in the absence of irreversible damage including myocardial necrosis. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.


Incretins are metabolic hormones that stimulate a decrease in glucose levels in the blood and they have been implicated in glycemic regulation in the remission phase of type 1 diabetes. Here is the latest research.

Chromatin Regulation and Circadian Clocks

The circadian clock plays an important role in regulating transcriptional dynamics through changes in chromatin folding and remodelling. Discover the latest research on Chromatin Regulation and Circadian Clocks here.

Long COVID-19

“Long Covid-19” describes illness in patients who are reporting long-lasting effects of the SARS-CoV-19 infection, often long after they have recovered from acute Covid-19. Ongoing health issues often reported include low exercise tolerance and breathing difficulties, chronic tiredness, and mental health problems such as post-traumatic stress disorder and depression. This feed follows the latest research into Long Covid.

Spatio-Temporal Regulation of DNA Repair

DNA repair is a complex process regulated by several different classes of enzymes, including ligases, endonucleases, and polymerases. This feed focuses on the spatial and temporal regulation that accompanies DNA damage signaling and repair enzymes and processes.