Long-term enhancement of dopamine release by high frequency tetanic stimulation via a N-methyl-D-aspartate-receptor-mediated pathway in rat striatum

Neuroscience
M OchiS Watanabe

Abstract

We studied the effects of high frequency tetanic stimulation of the striatum on the KCl (20 mM)-evoked dopamine release in rat striatal slices. The KCl-evoked dopamine release was potentiated by high frequency tetanic stimulation (10-20 Hz) of the striatum including the corticostriatal fibers, and this potentiation was observed until 3 h after high frequency tetanic stimulation. Potentiation of dopamine release after high frequency tetanic stimulation was induced not only by KCl but also by glutamate in Mg(2+)-free medium, N-methyl-D-aspartate in Mg(2+)-free medium, and by DL-alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid. 2-amino-5-phosphovalerate, 3-[(+/-)-2-carboxypiperazine-4-yl]-propyl-1-phosphonate or dibenzocycloheptaneimine, N-methyl-D-aspartate receptor inhibitors, abolished enhancement by tetanus, whereas, 6,7-dinitroquinoxaline-2,3-dione, an antagonist of DL-alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid ionotropic receptors, or L-2-amino-4-phosphonobutyrate, an antagonist of glutamate metabotropic receptors, showed no effect. Moreover, pretreatment with glutamate or N-methyl-D-aspartate in the absence of Mg2+ also facilitated dopamine release evoked by KCl concentrations. When extracellular Ca2...Continue Reading

References

Oct 26, 1979·Brain Research·J C Reubi, M Cuenod
Oct 23, 1990·European Journal of Pharmacology·A ImperatoL Angelucci
Aug 23, 1990·Nature·J M Bekkers, C F Stevens
Feb 1, 1986·Annals of Neurology·S M Rothman, J W Olney
Jan 1, 1989·Annual Review of Neuroscience·M Ito
Nov 1, 1974·Journal of Comparative and Physiological Psychology·J F MarshallP Teitelbaum
Oct 1, 1983·Brain Research·R J Beninger
Oct 1, 1977·Neuroscience Letters·M F GiorguieffJ Glowinski

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Citations

Mar 5, 2003·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Thomas G HedbergSolomon L Moshé
Feb 19, 2002·The European Journal of Neuroscience·Igor Mitrovic, T Celeste Napier
Jul 28, 2011·Journal of Toxicology and Environmental Health. Part B, Critical Reviews·Yoshinori Masuo, Masami Ishido
Jul 31, 2012·International Journal of Dentistry·Yoshihiro AbikoAkira Toyofuku
Sep 24, 2004·Journal of Neurochemistry·Yoshinori MasuoEtsuo Niki
Jul 6, 2007·The European Journal of Neuroscience·Yoshinori MasuoEtsuo Niki
Nov 6, 1998·Japanese Journal of Pharmacology·I AraiS Watanabe

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