Long-term evaluation of lipid profile and oral glucose tolerance test in Norplant users

Contraception
Fabio F AraujoEdmund C Baracat

Abstract

This study reports the results of the lipid profile and oral glucose tolerance test (OGTT) in 46 normal patients tested before and after 5 years of Norplant use. After 5 years, there was a substantial decrease of 28.9% in high-density lipoprotein cholesterol levels and a similar but less pronounced fall of 7.1% in the total cholesterol levels. The Castelli 1 index did not vary, and the triglycerides and low-density lipoprotein cholesterol levels remained normal and unchanged throughout the study period. All the mean values of OGTT were significantly lower after 5 years, except for the 90-min glycemia. These findings indicate that long-term Norplant use does not increase cardiovascular risks.

Citations

Nov 6, 2007·Clinical Obstetrics and Gynecology·Nathalie KappLynn Borgatta
Jul 13, 2007·Current Opinion in Obstetrics & Gynecology

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